2. Gene
  3. Pfkl - phosphofructokinase, liver, B-type Gene

Pfkl - phosphofructokinase, liver, B-type Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: PFK-B; PFK-L; ATP-PFK

基因 ID: 18641 | 基因类型: protein coding

关于 Pfkl

功能概要

Enables 6-phosphofructokinase activity. Acts upstream of or within several processes, including fructose 6-phosphate metabolic process; glycolytic process through fructose-6-phosphate; and negative regulation of Insulin secretion. Located in cytosol. Is expressed in several structures, including alimentary system; brain; genitourinary system; musculoskeletal system; and sensory organ. Orthologous to human PFKL (phosphofructokinase, liver type). [provided by Alliance of Genome Resources, Apr 2022]

Pfkl 基因产物(2)

mRNA Protein Name
NM_001358793.1 NP_001345722.1 ATP-dependent 6-phosphofructokinase, liver type isoform 2
NM_008826.5 NP_032852.2 ATP-dependent 6-phosphofructokinase, liver type isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables 6-phosphofructokinase activity IDA
IDA: 通过直接分析推断
6450202 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within fructose 6-phosphate metabolic process IDA
IDA: 通过直接分析推断
8172601 MGI
acts upstream of or within glycolytic process through fructose-6-phosphate IDA
IDA: 通过直接分析推断
8172601 MGI
involved in glycolytic process through fructose-6-phosphate IDA
IDA: 通过直接分析推断
8172601 MGI
involved in glycolytic process through fructose-6-phosphate IMP
IMP: 通过突变表型推断
35530161 MGI
acts upstream of or within negative regulation of insulin secretion IDA
IDA: 通过直接分析推断
9287040 MGI
acts upstream of or within response to glucose IDA
IDA: 通过直接分析推断
9287040 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytosol IDA
IDA: 通过直接分析推断
2521854 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ATP-dependent 6-phosphofructokinase, liver type

6-phosphofructokinase type B

6-phosphofructokinase, liver type

phosphofructo-1-kinase isozyme B

phosphofructokinase 1

phosphohexokinase

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10365 PFKL Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18781 Pfkl Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25270 Pfkl Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pfkl NCBI NCBI:5211
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