2. Gene
  3. Plg - plasminogen Gene

Plg - plasminogen Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Pg

基因 ID: 18815 | 基因类型: protein coding

关于 Plg

功能概要

Enables kinase binding activity. Involved in trans-synaptic signaling by BDNF, modulating synaptic transmission. Acts upstream of or within several processes, including embryonic placenta development; muscle cell cellular homeostasis; and myoblast differentiation. Located in Schaffer collateral - CA1 synapse and glutamatergic synapse. Is extrinsic component of plasma membrane. Is expressed in early conceptus; embryo; liver; and secondary oocyte. Human ortholog(s) of this gene implicated in COVID-19; conjunctivitis; myocardial infarction; plasminogen deficiency type I; and thrombophilia. Orthologous to several human genes including PLG (plasminogen). [provided by Alliance of Genome Resources, Apr 2022]

Plg 基因产物(1)

mRNA Protein Name
NM_008877.3 NP_032903.3 plasminogen precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables kinase binding IPI
IPI: 通过物理相互作用推断
24196407 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within labyrinthine layer blood vessel development IMP
IMP: 通过突变表型推断
12900459 MGI
acts upstream of or within mononuclear cell migration IMP
IMP: 通过突变表型推断
17690254 MGI
acts upstream of or within muscle cell cellular homeostasis IMP
IMP: 通过突变表型推断
11929773 MGI
acts upstream of or within myoblast differentiation IMP
IMP: 通过突变表型推断
11929773 MGI
acts upstream of or within protein processing IDA
IDA: 通过直接分析推断
34380733 MGI
acts upstream of or within tissue regeneration IMP
IMP: 通过突变表型推断
11929773 MGI
involved in trans-synaptic signaling by BDNF, modulating synaptic transmission IDA
IDA: 通过直接分析推断
15486301 MGI
involved in trans-synaptic signaling by BDNF, modulating synaptic transmission IEP
IEP: 通过表达模式推断
15486301 MGI
involved in trans-synaptic signaling by BDNF, modulating synaptic transmission IMP
IMP: 通过突变表型推断
15486301 MGI
acts upstream of or within trophoblast giant cell differentiation IMP
IMP: 通过突变表型推断
12900459 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in Schaffer collateral - CA1 synapse IDA
IDA: 通过直接分析推断
15486301 MGI
is active in Schaffer collateral - CA1 synapse IEP
IEP: 通过表达模式推断
15486301 MGI
is active in Schaffer collateral - CA1 synapse IMP
IMP: 通过突变表型推断
15486301 MGI
located in cell surface IDA
IDA: 通过直接分析推断
17690254 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
15486301 MGI
is active in glutamatergic synapse IEP
IEP: 通过表达模式推断
15486301 MGI
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
15486301 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

plasminogen

angiostatin

plasmin heavy chain A

plasmin light chain B

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-103423 PAOPA Modulator 98.09% 否
HY-RS10704 PLG Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16986 Plg Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23429 Plg Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Plg NCBI NCBI:5340
Canis familiaris Plg NCBI NCBI:403602
Macaca fascicularis Plg NCBI NCBI:102145643
Rattus norvegicus Plg NCBI NCBI:85253
Macaca mulatta Plg NCBI NCBI:703891
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