2. Gene
  3. Pou4f1 - POU domain, class 4, transcription factor 1 Gene

Pou4f1 - POU domain, class 4, transcription factor 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Brn3; Brn-3; Brn3a; Brn3.0; Brn-3.0; E130119J07Rik

基因 ID: 18996 | 基因类型: protein coding

关于 Pou4f1

功能概要

Enables several functions, including DNA binding activity; DNA-binding transcription activator activity, RNA polymerase II-specific; and GTPase binding activity. Involved in several processes, including cellular response to estradiol stimulus; nervous system development; and regulation of gene expression. Acts upstream of or within several processes, including nervous system development; proprioception involved in equilibrioception; and suckling behavior. Located in several cellular components, including chromatin; neuron projection; and nucleus. Part of RNA polymerase II transcription regulator complex. Is expressed in several structures, including branchial arch mesenchyme; central nervous system; future brain; ganglia; and retina. Orthologous to human POU4F1 (POU class 4 homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

Pou4f1 基因产物(1)

mRNA Protein Name
NM_011143.4 NP_035273.3 POU domain, class 4, transcription factor 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
12810599 MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
10329733 MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific IGI
IGI: 通过遗传相互作用推断
18421303 MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific IMP
IMP: 通过突变表型推断
12810599 MGI
enables DNA-binding transcription factor activity IMP
IMP: 通过突变表型推断
12810599 MGI
enables DNA-binding transcription factor activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
20096094 MGI
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IGI
IGI: 通过遗传相互作用推断
18421303 MGI
enables GTPase binding IPI
IPI: 通过物理相互作用推断
12934100 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
12810599 MGI
enables RNA polymerase II-specific DNA-binding transcription factor binding IPI
IPI: 通过物理相互作用推断
18421303 MGI
enables chromatin binding IGI
IGI: 通过遗传相互作用推断
12934100 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
8537352 MGI
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
7935408 MGI
enables single-stranded DNA binding IDA
IDA: 通过直接分析推断
8621561 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cell migration in hindbrain IMP
IMP: 通过突变表型推断
8955272 MGI
involved in cellular response to cytokine stimulus IDA
IDA: 通过直接分析推断
17668438 MGI
involved in cellular response to estradiol stimulus IDA
IDA: 通过直接分析推断
9448000 MGI
acts upstream of or within central nervous system neuron differentiation IMP
IMP: 通过突变表型推断
8876243 MGI
acts upstream of or within habenula development IMP
IMP: 通过突变表型推断
19906978 MGI
involved in heart development IGI
IGI: 通过遗传相互作用推断
28594399 MGI
acts upstream of or within innervation IMP
IMP: 通过突变表型推断
19906978 MGI
involved in intrinsic apoptotic signaling pathway by p53 class mediator IMP
IMP: 通过突变表型推断
17145718 MGI
acts upstream of or within mesoderm development IMP
IMP: 通过突变表型推断
19877281 MGI
acts upstream of negative regulation of apoptotic process IGI
IGI: 通过遗传相互作用推断
18421303 MGI
involved in negative regulation of apoptotic process IGI
IGI: 通过遗传相互作用推断
12203124 MGI
involved in negative regulation of gene expression IMP
IMP: 通过突变表型推断
28594399 MGI
involved in negative regulation of neuron apoptotic process IMP
IMP: 通过突变表型推断
20096094 MGI
involved in negative regulation of programmed cell death IMP
IMP: 通过突变表型推断
17145718 MGI
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
19877281 MGI
involved in negative regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
18421303 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
19877281 MGI
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
17239249 MGI
acts upstream of or within nervous system development IDA
IDA: 通过直接分析推断
12810599 MGI
acts upstream of neuron apoptotic process IGI
IGI: 通过遗传相互作用推断
15492043 MGI
acts upstream of or within neuron differentiation IMP
IMP: 通过突变表型推断
16040009 MGI
involved in neuron fate specification IMP
IMP: 通过突变表型推断
19877281 MGI
acts upstream of or within neuron migration IMP
IMP: 通过突变表型推断
8955272 MGI
involved in neuron projection development IDA
IDA: 通过直接分析推断
8972215 MGI
acts upstream of or within peripheral nervous system neuron development IGI
IGI: 通过遗传相互作用推断
21734270 MGI
involved in peripheral nervous system neuron development IMP
IMP: 通过突变表型推断
17239249 MGI
acts upstream of or within peripheral nervous system neuron differentiation IMP
IMP: 通过突变表型推断
8876243 MGI
involved in positive regulation of gene expression IDA
IDA: 通过直接分析推断
8972215 MGI
acts upstream of or within positive regulation of neuron apoptotic process IGI
IGI: 通过遗传相互作用推断
15492043 MGI
involved in positive regulation of osteoclast differentiation IMP
IMP: 通过突变表型推断
17668438 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
10329733 MGI
involved in positive regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
12934100 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
19877281 MGI
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
7935408 MGI
involved in positive regulation of transcription regulatory region DNA binding IDA
IDA: 通过直接分析推断
9448000 MGI
acts upstream of or within proprioception involved in equilibrioception IMP
IMP: 通过突变表型推断
8876243 MGI
involved in regulation of DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
9448000 MGI
acts upstream of or within regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
12810599 MGI
acts upstream of regulation of cell cycle IGI
IGI: 通过遗传相互作用推断
12203124 MGI
acts upstream of negative effect regulation of cell cycle IGI
IGI: 通过遗传相互作用推断
18421303 MGI
involved in regulation of cell cycle IMP
IMP: 通过突变表型推断
17145718 MGI
acts upstream of or within regulation of neurogenesis IMP
IMP: 通过突变表型推断
19877281 MGI
involved in sensory system development IMP
IMP: 通过突变表型推断
20096094 MGI
acts upstream of or within suckling behavior IMP
IMP: 通过突变表型推断
8876243 MGI
involved in trigeminal nerve development IMP
IMP: 通过突变表型推断
19877281 MGI
involved in ventricular compact myocardium morphogenesis IMP
IMP: 通过突变表型推断
18368538 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of RNA polymerase II transcription regulator complex IDA
IDA: 通过直接分析推断
10329733 MGI
located in chromatin IDA
IDA: 通过直接分析推断
17196582 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
17668438 MGI
located in neuron projection IDA
IDA: 通过直接分析推断
19906978 MGI
located in nucleus IDA
IDA: 通过直接分析推断
7623109 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

POU domain, class 4, transcription factor 1

brain-3A

brain-specific homeobox/POU domain protein 3A

brn-3A

Pou4f1 抗体

目录号 产品名 应用 反应物种
HY-P86792 BRN3A Antibody (YA6485) IHC-F, IHC-P Mouse
HY-P86793 BRN3A Antibody (YA6486) IHC-F, IHC-P, WB Mouse, Rat

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10904 POU4F1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21173 Pou4f1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27690 Pou4f1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pou4f1 NCBI NCBI:5457
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