2. Gene
  3. Prkg1 - protein kinase, cGMP-dependent, type I Gene

Prkg1 - protein kinase, cGMP-dependent, type I Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: CGKI; Prkg1b; Gm19690; Prkgr1b

基因 ID: 19091 | 基因类型: protein coding

关于 Prkg1

功能概要

Enables cGMP binding activity and cGMP-dependent protein kinase activity. Involved in protein phosphorylation and signal transduction. Acts upstream of or within cGMP-mediated signaling; nervous system development; and relaxation of vascular associated smooth muscle. Located in Golgi apparatus and plasma membrane. Is expressed in several structures, including bone; central nervous system; genitourinary system; gut; and respiratory system. Human ortholog(s) of this gene implicated in thoracic aortic aneurysm. Orthologous to human PRKG1 (protein kinase cGMP-dependent 1). [provided by Alliance of Genome Resources, Apr 2022]

Prkg1 基因产物(3)

mRNA Protein Name
NM_001013833.3 NP_001013855.1 cGMP-dependent protein kinase 1 isoform alpha
NM_001411181.1 NP_001398110.1 cGMP-dependent protein kinase 1 isoform alpha
NM_011160.3 NP_035290.1 cGMP-dependent protein kinase 1 isoform beta
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables cGMP binding IDA
IDA: 通过直接分析推断
10671526 MGI
enables cGMP-dependent protein kinase activity IDA
IDA: 通过直接分析推断
10671526 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
10671526 MGI
enables protein kinase activity IDA
IDA: 通过直接分析推断
10671526 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cGMP-mediated signaling IMP
IMP: 通过突变表型推断
15483626 MGI
involved in collateral sprouting IMP
IMP: 通过突变表型推断
17954614 MGI
acts upstream of or within dendrite development IMP
IMP: 通过突变表型推断
16154207 MGI
acts upstream of or within forebrain development IMP
IMP: 通过突变表型推断
16154207 MGI
acts upstream of or within negative regulation of smooth muscle contraction IMP
IMP: 通过突变表型推断
15483626 MGI
acts upstream of or within neuron migration IMP
IMP: 通过突变表型推断
16154207 MGI
involved in protein phosphorylation IDA
IDA: 通过直接分析推断
10671526 MGI
acts upstream of or within relaxation of vascular associated smooth muscle IMP
IMP: 通过突变表型推断
15483626 MGI
involved in signal transduction IDA
IDA: 通过直接分析推断
10671526 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Golgi apparatus IDA
IDA: 通过直接分析推断
10671526 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
16990611 MGI
located in plasma membrane IMP
IMP: 通过突变表型推断
19127022 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

cGMP-dependent protein kinase 1

cGK 1

cGK1

cGMP-dependent protein kinase I

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11154 PRKG1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20087 Prkg1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26590 Prkg1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Prkg1 NCBI NCBI:5592
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