2. Gene
  3. Prom1 - prominin 1 Gene

Prom1 - prominin 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Prom; AC133; CD133; Prom-1; Proml1; 4932416E19Rik

基因 ID: 19126 | 基因类型: protein coding

关于 Prom1

功能概要

Predicted to enable actinin binding activity; Cadherin binding activity; and Cholesterol binding activity. Involved in camera-type eye photoreceptor cell differentiation and retina layer formation. Located in several cellular components, including brush border; photoreceptor outer segment; and prominosome. Is integral component of plasma membrane. Is expressed in several structures, including epithelium; eye; future hindbrain; genitourinary system; and nervous system. Used to study retinitis pigmentosa 41. Human ortholog(s) of this gene implicated in cone-rod dystrophy 12 and retinitis pigmentosa 41. Orthologous to human PROM1 (prominin 1). [provided by Alliance of Genome Resources, Apr 2022]

Prom1 基因产物(8)

mRNA Protein Name
NM_001163577.1 NP_001157049.1 prominin-1 isoform s2 precursor
NM_001163578.1 NP_001157050.1 prominin-1 isoform s3 precursor
NM_001163581.1 NP_001157053.1 prominin-1 isoform s4 precursor
NM_001163582.1 NP_001157054.1 prominin-1 isoform s5 precursor
NM_001163583.1 NP_001157055.1 prominin-1 isoform s6 precursor
NM_001163584.1 NP_001157056.1 prominin-1 isoform s7 precursor
NM_001163585.1 NP_001157057.1 prominin-1 isoform s8 precursor
NM_008935.2 NP_032961.2 prominin-1 isoform s1 precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in camera-type eye photoreceptor cell differentiation IMP
IMP: 通过突变表型推断
19228982 MGI
involved in retina layer formation IMP
IMP: 通过突变表型推断
19228982 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical plasma membrane IDA
IDA: 通过直接分析推断
16892058 MGI
located in brush border IDA
IDA: 通过直接分析推断
9356465 MGI
located in cell projection IDA
IDA: 通过直接分析推断
10587575 MGI
located in cilium IDA
IDA: 通过直接分析推断
17109118 MGI
located in extracellular space IDA
IDA: 通过直接分析推断
15976444 MGI
located in microvillus IDA
IDA: 通过直接分析推断
9356465 MGI
located in photoreceptor outer segment IDA
IDA: 通过直接分析推断
19228982 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
9356465 MGI
located in prominosome IDA
IDA: 通过直接分析推断
15976444 MGI
located in stereocilium IDA
IDA: 通过直接分析推断
15316084 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

prominin-1

antigen AC133 homolog

prominin-like 1

prominin-like protein 1

Prom1 抗体

目录号 产品名 应用 反应物种
HY-P86802 CD133 Antibody (YA6495) WB, IHC-P, IHC-F Mouse

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11198 PROM1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17613 Prom1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24073 Prom1 Rat Pre-designed siRNA Set A Pre-designed Set / 否
抗体抑制剂 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P991431 Anti-CD133/PROM1 Antibody (CMab-43) Inhibitor / 否
HY-P991463 MS133 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Prom1 NCBI NCBI:8842
Rattus norvegicus Prom1 NCBI NCBI:60357
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