2. Gene
  3. St14 - suppression of tumorigenicity 14 (colon carcinoma) Gene

St14 - suppression of tumorigenicity 14 (colon carcinoma) Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: mCAP3; MT-SP1; Prss14; Epithin; Tmprss14; matriptase

基因 ID: 19143 | 基因类型: protein coding

关于 St14

功能概要

Enables serine-type endopeptidase activity. Acts upstream of or within epithelial cell morphogenesis involved in placental branching and neural tube closure. Located in extracellular region. Is extrinsic component of plasma membrane. Is expressed in several structures, including alimentary system; early conceptus; genitourinary system; pituitary gland; and sensory organ. Used to study Sjogren's syndrome. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 11. Orthologous to human ST14 (ST14 transmembrane serine protease matriptase). [provided by Alliance of Genome Resources, Apr 2022]

St14 基因产物(1)

mRNA Protein Name
NM_011176.4 NP_035306.2 suppressor of tumorigenicity 14 protein homolog
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables serine-type endopeptidase activity EXP
EXP: 通过实验结果推断
20657595 MGI
enables serine-type peptidase activity IDA
IDA: 通过直接分析推断
11567025 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within epithelial cell morphogenesis involved in placental branching IGI
IGI: 通过遗传相互作用推断
19592578 MGI
acts upstream of or within neural tube closure IGI
IGI: 通过遗传相互作用推断
19592578 MGI
involved in proteolysis IDA
IDA: 通过直接分析推断
11567025 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
11567025 MGI
located in extracellular space IDA
IDA: 通过直接分析推断
11567025 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

suppressor of tumorigenicity 14 protein homolog

matriptase/MT-SP1

protease, serine, 14 (epithin)

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS17968 St14 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS13844 ST14 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24439 St14 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens St14 NCBI NCBI:6768
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