2. Gene
  3. Ptch2 - patched 2 Gene

Ptch2 - patched 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: ptc2

基因 ID: 19207 | 基因类型: protein coding

关于 Ptch2

功能概要

This gene encodes a member of the patched family of transmembrane Receptor Proteins. The encoded protein may be a functional receptor for the morphogen sonic Hedgehog (Shh) and is reportedly involved in limb and skin development. Homozygous mutant mice for this gene exhibit hair loss and epidermal hyperplasia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]

Ptch2 基因产物(2)

mRNA Protein Name
NM_001312903.1 NP_001299832.1 protein patched homolog 2 isoform 2
NM_008958.3 NP_032984.1 protein patched homolog 2 isoform 1
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cell fate determination IGI
IGI: 通过遗传相互作用推断
24492243 MGI
acts upstream of or within epidermal cell fate specification IGI
IGI: 通过遗传相互作用推断
24492243 MGI
acts upstream of or within epidermis development IMP
IMP: 通过突变表型推断
16914743 MGI
acts upstream of or within hair cycle IMP
IMP: 通过突变表型推断
16914743 MGI
acts upstream of or within positive regulation of epidermal cell differentiation IGI
IGI: 通过遗传相互作用推断
24492243 MGI
acts upstream of or within skin development IMP
IMP: 通过突变表型推断
16914743 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

protein patched homolog 2

patched homolog 2

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11357 PTCH2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22751 Ptch2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25164 Ptch1 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS29265 Ptch2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ptch2 NCBI NCBI:8643
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