2. Gene
  3. Ptger4 - prostaglandin E receptor 4 (subtype EP4) Gene

Ptger4 - prostaglandin E receptor 4 (subtype EP4) Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: EP4; Ptgerep4

基因 ID: 19219 | 基因类型: protein coding

关于 Ptger4

功能概要

Predicted to enable prostaglandin E receptor activity. Involved in several processes, including T-helper cell differentiation; regulation of cytokine production; and regulation of stress fiber assembly. Acts upstream of or within several processes, including cellular response to mechanical stimulus; regulation of ossification; and response to lipopolysaccharide. Predicted to be located in neuron projection terminus; neuronal cell body; and nuclear membrane. Predicted to be active in plasma membrane. Is expressed in central nervous system; early conceptus; heart valve; retina; and secondary oocyte. Used to study dilated cardiomyopathy. Human ortholog(s) of this gene implicated in ankylosing spondylitis; arteriosclerosis; and ulcerative colitis. Orthologous to human PTGER4 (prostaglandin E receptor 4). [provided by Alliance of Genome Resources, Apr 2022]

Ptger4 基因产物(2)

mRNA Protein Name
NM_001136079.2 NP_001129551.1 prostaglandin E2 receptor EP4 subtype isoform 1
NM_008965.2 NP_032991.1 prostaglandin E2 receptor EP4 subtype isoform 2
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in T-helper cell differentiation IDA
IDA: 通过直接分析推断
19465928 MGI
involved in cellular response to mechanical stimulus IEP
IEP: 通过表达模式推断
14665434 MGI
acts upstream of or within interleukin-33 production IMP
IMP: 通过突变表型推断
32484881 MGI
involved in negative regulation of cytokine production IMP
IMP: 通过突变表型推断
11602631 MGI
acts upstream of or within negative regulation of inflammatory response IGI
IGI: 通过遗传相互作用推断
18270204 MGI
acts upstream of or within negative regulation of inflammatory response IMP
IMP: 通过突变表型推断
18270204 MGI
involved in positive regulation of cytokine production IDA
IDA: 通过直接分析推断
19465928 MGI
involved in positive regulation of inflammatory response IDA
IDA: 通过直接分析推断
19465928 MGI
acts upstream of or within regulation of ossification IMP
IMP: 通过突变表型推断
10749873 MGI
involved in regulation of stress fiber assembly IDA
IDA: 通过直接分析推断
14665434 MGI
acts upstream of or within response to lipopolysaccharide IMP
IMP: 通过突变表型推断
15834430 MGI
acts upstream of or within response to nematode IMP
IMP: 通过突变表型推断
32484881 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

prostaglandin E2 receptor EP4 subtype

PGE2 receptor EP4 subtype

prostanoid EP4 receptor

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11378 PTGER4 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18874 Ptger4 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25365 Ptger4 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ptger4 NCBI NCBI:5734
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