1. Gene
  2. Ptgr1 - prostaglandin reductase 1 Gene

Ptgr1 - prostaglandin reductase 1 Gene

种属: Rattus norvegicus

同用名: Dig1; Ltb4dh

基因 ID: 192227 | 基因类型: protein coding

关于 Ptgr1

功能概要

Enables 13-prostaglandin reductase activity and 2-alkenal reductase (NADP+) activity. Involved in response to antineoplastic agent. Predicted to be located in cytoplasm. Orthologous to human PTGR1 (prostaglandin reductase 1). [provided by Alliance of Genome Resources, Apr 2022]

Ptgr1 基因产物(1)

mRNA Protein Name
NM_138863.2 NP_620218.1 prostaglandin reductase 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables 15-oxoprostaglandin 13-oxidase [NAD(P)+] activity IDA
IDA: 通过直接分析推断
11524419 RGD
enables 2-alkenal reductase (NADPH) activity IDA
IDA: 通过直接分析推断
11524419 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular alkene metabolic process IDA
IDA: 通过直接分析推断
11524419 RGD
involved in leukotriene B4 metabolic process IDA
IDA: 通过直接分析推断
9667737 RGD
involved in negative regulation of positive chemotaxis IDA
IDA: 通过直接分析推断
9667737 RGD
involved in negative regulation of reactive oxygen species biosynthetic process IDA
IDA: 通过直接分析推断
9667737 RGD
involved in response to antineoplastic agent IEP
IEP: 通过表达模式推断
8968041 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
24853774 RGD
located in cytosol IDA
IDA: 通过直接分析推断
9667737 RGD
located in nucleus IDA
IDA: 通过直接分析推断
24853774 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

prostaglandin reductase 1

15-oxoprostaglandin 13-reductase

D3T-inducible gene 1 protein

DIG-1

NAD(P)H-dependent alkenal/one oxidoreductase

NADP-dependent leukotriene B4 12-hydroxydehydrogenase

PRG-1

dithiolethione-inducible gene 1 protein

dithiolethione-inducible gene-1

le

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ptgr1 NCBI NCBI:22949