1. Gene
  2. Purb - purine rich element binding protein B Gene

Purb - purine rich element binding protein B Gene

种属: Mus musculus

同用名: Cager-2; D11Bwg0414e; 2310015K15Rik

基因 ID: 19291 | 基因类型: protein coding

关于 Purb

功能概要

Enables several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; SMAD binding activity; and nucleic acid binding activity. Involved in negative regulation of transcription by RNA polymerase II. Acts upstream of or within negative regulation of transcription, DNA-templated. Located in nucleus. Is expressed in heart and hindlimb muscle. Orthologous to human PURB (purine rich element binding protein B). [provided by Alliance of Genome Resources, Apr 2022]

Purb 基因产物(1)

mRNA Protein Name
NM_011221.3 NP_035351.1 transcriptional activator protein Pur-beta
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
15282343 MGI
enables DNA-binding transcription factor binding IPI
IPI: 通过物理相互作用推断
10318844 MGI
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
15282343 MGI
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IMP
IMP: 通过突变表型推断
27064749 MGI
enables RNA binding IDA
IDA: 通过直接分析推断
23723417 MGI
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
15282343 MGI
enables SMAD binding IDA
IDA: 通过直接分析推断
15282343 MGI
enables double-stranded DNA binding IDA
IDA: 通过直接分析推断
15282343 MGI
enables mRNA binding IDA
IDA: 通过直接分析推断
12933792 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
15282343 MGI
enables single-stranded DNA binding IDA
IDA: 通过直接分析推断
10318844 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
15282343 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

transcriptional activator protein Pur-beta

PurB beta

purine-rich single-stranded DNA-binding protein beta

vascular actin single-stranded DNA-binding factor 2 p44 component

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Purb NCBI NCBI:5814