2. Gene
  3. Rad21 - RAD21 cohesin complex component Gene

Rad21 - RAD21 cohesin complex component Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: SCC1; mHR21; mKIAA0078

基因 ID: 19357 | 基因类型: protein coding

关于 Rad21

功能概要

Predicted to enable chromatin binding activity. Involved in negative regulation of G2/M transition of mitotic cell cycle and negative regulation of mitotic metaphase/anaphase transition. Located in chromatin; chromosome, centromeric region; and condensed nuclear chromosome. Part of cohesin complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome 4; hepatocellular carcinoma; and lung non-small cell carcinoma. Orthologous to human RAD21 (RAD21 cohesin complex component). [provided by Alliance of Genome Resources, Apr 2022]

Rad21 基因产物(2)

mRNA Protein Name
NM_001411716.1 NP_001398645.1 double-strand-break repair protein rad21 homolog
NM_009009.5 NP_033035.3 double-strand-break repair protein rad21 homolog
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
28636939 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
10375619 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within chromatin looping IMP
IMP: 通过突变表型推断
32328639 MGI
involved in negative regulation of G2/M transition of mitotic cell cycle IMP
IMP: 通过突变表型推断
10375619 MGI
involved in negative regulation of mitotic metaphase/anaphase transition IMP
IMP: 通过突变表型推断
10375619 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in chromatin IDA
IDA: 通过直接分析推断
23920377 MGI
located in chromosome, centromeric region IDA
IDA: 通过直接分析推断
26919979 MGI
part of cohesin complex IDA
IDA: 通过直接分析推断
10375619 MGI
located in condensed nuclear chromosome IDA
IDA: 通过直接分析推断
24797475 MGI
located in nucleus IDA
IDA: 通过直接分析推断
10375619 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

double-strand-break repair protein rad21 homolog

PW29

RAD21 homolog

SCC1 homolog

pokeweed agglutinin-binding protein 29

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P10931F RAD21 (356–395), biotin labeled / 否
HY-RS11599 RAD21 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20093 Rad21 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26596 Rad21 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rad21 NCBI NCBI:5885
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