2. Gene
  3. Hspa1a - heat shock protein 1A Gene

Hspa1a - heat shock protein 1A Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Hsp72; hsp68; Hsp70-3; Hsp70.3; hsp70A1

基因 ID: 193740 | 基因类型: protein coding

关于 Hspa1a

功能概要

Enables protein folding chaperone. Involved in lysosomal transport and protein folding. Acts upstream of or within DNA repair; response to heat; and telomere maintenance. Located in cytoplasm. Is expressed in several structures, including adrenal gland; early conceptus; genitourinary system; and vibrissa. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; autoimmune disease of musculoskeletal system (multiple); cystic fibrosis; schizophrenia (multiple); and toxic shock syndrome. Orthologous to several human genes including HSPA1B (heat shock protein family A (HSP70) member 1B). [provided by Alliance of Genome Resources, Apr 2022]

Hspa1a 基因产物(1)

mRNA Protein Name
NM_010479.2 NP_034609.2 heat shock 70 kDa protein 1A
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
19052621 MGI
enables protein folding chaperone IDA
IDA: 通过直接分析推断
27496612 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within DNA repair IMP
IMP: 通过突变表型推断
14701760 MGI
involved in lysosomal transport IMP
IMP: 通过突变表型推断
27789271 MGI
involved in protein folding IDA
IDA: 通过直接分析推断
27496612 MGI
acts upstream of or within response to heat IDA
IDA: 通过直接分析推断
18755693 MGI
acts upstream of or within response to heat IMP
IMP: 通过突变表型推断
14701760 MGI
acts upstream of or within telomere maintenance IMP
IMP: 通过突变表型推断
14701760 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
16906134 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

heat shock 70 kDa protein 1A

68 kDa heat shock protein

heat shock 70 kDa protein 3

heat shock 70kDa protein 1A

heat shock protein, 70 kDa 3

inducible heat shock protein 70

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06424 HSPA1A Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18094 Hspa1a Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24569 Hspa1a Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hspa1a NCBI NCBI:3303
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