2. Gene
  3. Rdx - radixin Gene

Rdx - radixin Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

基因 ID: 19684 | 基因类型: protein coding

关于 Rdx

功能概要

Enables protein domain specific binding activity. Involved in cellular response to thyroid hormone stimulus; establishment of protein localization; and positive regulation of G1/S transition of mitotic cell cycle. Acts upstream of or within apical protein localization and microvillus assembly. Located in several cellular components, including lamellipodium; microvillus; and ruffle. Colocalizes with plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and sensory organ. Used to study Dubin-Johnson syndrome. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 24. Orthologous to human RDX (radixin). [provided by Alliance of Genome Resources, Apr 2022]

Rdx 基因产物(3)

mRNA Protein Name
NM_001104616.1 NP_001098086.1 radixin isoform a
NM_001104617.1 NP_001098087.1 radixin isoform b
NM_009041.3 NP_033067.2 radixin isoform a
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
9472040 MGI
enables protein domain specific binding IPI
IPI: 通过物理相互作用推断
21047789 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within apical protein localization IMP
IMP: 通过突变表型推断
12068294 MGI
involved in cellular response to thyroid hormone stimulus IMP
IMP: 通过突变表型推断
21047789 MGI
involved in establishment of protein localization IMP
IMP: 通过突变表型推断
21047789 MGI
acts upstream of or within microvillus assembly IMP
IMP: 通过突变表型推断
12068294 MGI
involved in positive regulation of G1/S transition of mitotic cell cycle IMP
IMP: 通过突变表型推断
21047789 MGI
involved in regulation of postsynaptic neurotransmitter receptor diffusion trapping IDA
IDA: 通过直接分析推断
25891999 MGI
involved in regulation of postsynaptic neurotransmitter receptor diffusion trapping IMP
IMP: 通过突变表型推断
25891999 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical part of cell IDA
IDA: 通过直接分析推断
9890997 MGI
located in cortical actin cytoskeleton IDA
IDA: 通过直接分析推断
21047789 MGI
located in filopodium IDA
IDA: 通过直接分析推断
9563848 MGI
located in lamellipodium IDA
IDA: 通过直接分析推断
9563848 MGI
located in microvillus IDA
IDA: 通过直接分析推断
9472040 MGI
colocalizes with plasma membrane IDA
IDA: 通过直接分析推断
21047789 MGI
located in ruffle IDA
IDA: 通过直接分析推断
9563848 MGI
located in stereocilium IDA
IDA: 通过直接分析推断
17021174 MGI
located in stereocilium base IDA
IDA: 通过直接分析推断
24285636 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

radixin

ESP10

相关产品

Approval
生物活性分子 (2)
目录号 产品名 作用方式
纯度 是否罕见病
HY-15991 Tenapanor Inhibitor 99.65% 否
HY-15991A Tenapanor hydrochloride Inhibitor 99.55% 否
Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-13631J (1R,9R)-Exatecan mesylate 99.94% 否
HY-13631I (1S,9R)-Exatecan mesylate 98.23% 否
HY-P2800 Diaphorase, Recombinant microorganisms / 否
HY-RS11806 RDX Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18121 Rdx Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24595 Rdx Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rdx NCBI NCBI:5962
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