2. Gene
  3. Reln - reelin Gene

Reln - reelin Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: rl; reeler

基因 ID: 19699 | 基因类型: protein coding

关于 Reln

功能概要

Enables very-low-density lipoprotein particle receptor binding activity. Involved in several processes, including positive regulation of cell communication; postsynaptic membrane organization; and regulation of neurotransmitter receptor activity. Acts upstream of or within several processes, including nervous system development; peptidyl-tyrosine phosphorylation; and thyroid hormone metabolic process. Located in several cellular components, including dendrite; extracellular matrix; and extracellular space. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and sensory organ. Used to study schizophrenia. Human ortholog(s) of this gene implicated in Norman-Roberts syndrome; autistic disorder; and familial temporal lobe epilepsy 7. Orthologous to human RELN (reelin). [provided by Alliance of Genome Resources, Apr 2022]

Reln 基因产物(2)

mRNA Protein Name
NM_001310464.1 NP_001297393.1 reelin isoform 2 precursor
NM_011261.2 NP_035391.2 reelin isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables lipoprotein particle receptor binding IPI
IPI: 通过物理相互作用推断
10571240 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
10571241 MGI
enables receptor ligand activity IDA
IDA: 通过直接分析推断
10571241 MGI
enables serine-type peptidase activity IDA
IDA: 通过直接分析推断
11689558 MGI
enables very-low-density lipoprotein particle receptor binding IPI
IPI: 通过物理相互作用推断
10571240 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in NMDA glutamate receptor clustering IMP
IMP: 通过突变表型推断
21664258 MGI
involved in associative learning IDA
IDA: 通过直接分析推断
21852430 MGI
involved in associative learning IMP
IMP: 通过突变表型推断
21852430 MGI
acts upstream of or within axon guidance IMP
IMP: 通过突变表型推断
16324103 MGI
acts upstream of or within brain development IMP
IMP: 通过突变表型推断
12223565 MGI
acts upstream of or within cell migration IMP
IMP: 通过突变表型推断
17694053 MGI
acts upstream of or within cell morphogenesis IMP
IMP: 通过突变表型推断
12925587 MGI
acts upstream of or within central nervous system development IMP
IMP: 通过突变表型推断
11900467 MGI
acts upstream of or within cerebral cortex development IMP
IMP: 通过突变表型推断
21491433 MGI
acts upstream of or within cerebral cortex tangential migration IMP
IMP: 通过突变表型推断
16901480 MGI
acts upstream of or within dendrite development IGI
IGI: 通过遗传相互作用推断
14715136 MGI
acts upstream of or within dendrite development IMP
IMP: 通过突变表型推断
14715136 MGI
acts upstream of or within forebrain development IMP
IMP: 通过突变表型推断
17694053 MGI
acts upstream of or within glial cell differentiation IMP
IMP: 通过突变表型推断
12925587 MGI
involved in hippocampus development IDA
IDA: 通过直接分析推断
17229826 MGI
acts upstream of or within interneuron migration IMP
IMP: 通过突变表型推断
14980731 MGI
involved in lateral motor column neuron migration IMP
IMP: 通过突变表型推断
20711475 MGI
involved in layer formation in cerebral cortex IDA
IDA: 通过直接分析推断
10880573 MGI
acts upstream of or within layer formation in cerebral cortex IMP
IMP: 通过突变表型推断
20847152 MGI
involved in learning IMP
IMP: 通过突变表型推断
21852430 MGI
acts upstream of or within locomotory behavior IMP
IMP: 通过突变表型推断
24539699 MGI
involved in long-term memory IDA
IDA: 通过直接分析推断
21852430 MGI
involved in long-term memory IMP
IMP: 通过突变表型推断
21852430 MGI
involved in long-term synaptic potentiation IMP
IMP: 通过突变表型推断
21852430 MGI
involved in modulation of chemical synaptic transmission IMP
IMP: 通过突变表型推断
18778775 MGI
acts upstream of or within motor neuron migration IMP
IMP: 通过突变表型推断
15703280 MGI
acts upstream of or within neuron migration IGI
IGI: 通过遗传相互作用推断
11226314 MGI
acts upstream of or within neuron migration IMP
IMP: 通过突变表型推断
12223565 MGI
acts upstream of or within peptidyl-tyrosine phosphorylation IDA
IDA: 通过直接分析推断
12526740 MGI
involved in positive regulation of AMPA receptor activity IMP
IMP: 通过突变表型推断
17229826 MGI
involved in positive regulation of CREB transcription factor activity IMP
IMP: 通过突变表型推断
21852430 MGI
involved in positive regulation of TOR signaling IDA
IDA: 通过直接分析推断
21664258 MGI
involved in positive regulation of dendritic spine morphogenesis IDA
IDA: 通过直接分析推断
21852430 MGI
involved in positive regulation of dendritic spine morphogenesis IMP
IMP: 通过突变表型推断
21664258 MGI
involved in positive regulation of excitatory postsynaptic potential IDA
IDA: 通过直接分析推断
17229826 MGI
involved in positive regulation of excitatory postsynaptic potential IMP
IMP: 通过突变表型推断
17229826 MGI
involved in positive regulation of lateral motor column neuron migration IMP
IMP: 通过突变表型推断
20711475 MGI
involved in positive regulation of long-term synaptic potentiation IDA
IDA: 通过直接分析推断
21852430 MGI
involved in positive regulation of neuron projection development IMP
IMP: 通过突变表型推断
17229826 MGI
involved in positive regulation of peptidyl-tyrosine phosphorylation IDA
IDA: 通过直接分析推断
10571240 MGI
involved in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IDA
IDA: 通过直接分析推断
21664258 MGI
acts upstream of or within positive regulation of protein kinase activity IDA
IDA: 通过直接分析推断
12526740 MGI
acts upstream of or within positive regulation of protein kinase activity IGI
IGI: 通过遗传相互作用推断
12526740 MGI
involved in positive regulation of protein tyrosine kinase activity IMP
IMP: 通过突变表型推断
21852430 MGI
acts upstream of or within positive regulation of small GTPase mediated signal transduction IDA
IDA: 通过直接分析推断
15062102 MGI
involved in positive regulation of synapse maturation IDA
IDA: 通过直接分析推断
17229826 MGI
involved in positive regulation of synapse maturation IMP
IMP: 通过突变表型推断
17229826 MGI
involved in positive regulation of synaptic transmission, glutamatergic IDA
IDA: 通过直接分析推断
17229826 MGI
involved in positive regulation of synaptic transmission, glutamatergic IMP
IMP: 通过突变表型推断
17229826 MGI
involved in postsynaptic density assembly IMP
IMP: 通过突变表型推断
21664258 MGI
involved in postsynaptic density protein 95 clustering IMP
IMP: 通过突变表型推断
21664258 MGI
involved in protein localization to synapse IMP
IMP: 通过突变表型推断
21664258 MGI
involved in receptor localization to synapse IMP
IMP: 通过突变表型推断
21664258 MGI
involved in reelin-mediated signaling pathway IDA
IDA: 通过直接分析推断
10571240 MGI
involved in regulation of NMDA receptor activity IMP
IMP: 通过突变表型推断
20357114 MGI
involved in regulation of behavior IMP
IMP: 通过突变表型推断
20357114 MGI
acts upstream of or within regulation of gene expression IMP
IMP: 通过突变表型推断
15255972 MGI
involved in regulation of synapse maturation IDA
IDA: 通过直接分析推断
27624722 MGI
involved in regulation of synapse maturation IMP
IMP: 通过突变表型推断
27624722 MGI
acts upstream of or within response to pain IMP
IMP: 通过突变表型推断
16580148 MGI
acts upstream of or within spinal cord patterning IMP
IMP: 通过突变表型推断
16580148 MGI
involved in ventral spinal cord development IEP
IEP: 通过表达模式推断
20711475 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
15525772 MGI
located in dendrite IDA
IDA: 通过直接分析推断
15677725 MGI
located in extracellular matrix IDA
IDA: 通过直接分析推断
22665518 MGI
is active in extracellular space IDA
IDA: 通过直接分析推断
8987733 MGI
located in extracellular space IDA
IDA: 通过直接分析推断
10939329 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

reelin

extracellular matrix serine protease

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11835 RELN Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18151 Reln Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24626 Reln Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Reln NCBI NCBI:5649
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z