2. Gene
  3. Rpe65 - retinal pigment epithelium 65 Gene

Rpe65 - retinal pigment epithelium 65 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: LCA2; RP20; rd12; 65kDa; Mord1; A930029L06Rik

基因 ID: 19892 | 基因类型: protein coding

关于 Rpe65

功能概要

Enables retinal isomerase activity. Acts upstream of or within several processes, including cellular response to electrical stimulus; Insulin Receptor signaling pathway; and retinal metabolic process. Located in cytoplasm; nucleus; and plasma membrane. Is expressed in eye; pelvic urothelial lining; pigmented retinal epithelium; and urothelium of ureter. Used to study Leber congenital amaurosis 2 and retinitis pigmentosa 20. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 2; retinitis pigmentosa; retinitis pigmentosa 20; and retinitis pigmentosa 87. Orthologous to human RPE65 (retinoid isomerohydrolase RPE65). [provided by Alliance of Genome Resources, Apr 2022]

Rpe65 基因产物(1)

mRNA Protein Name
NM_029987.2 NP_084263.2 retinoid isomerohydrolase
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
21493626 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
26404741 MGI
located in nucleus IDA
IDA: 通过直接分析推断
26404741 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
26404741 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

retinoid isomerohydrolase

all-trans-retinyl-palmitate hydrolase

lutein isomerase

meso-zeaxanthin isomerase

modifier of retinal degeneration 1

retinal pigment epithelium, 65 kDa

retinal pigment epithelium-specific 65 kDa protein

retinol isomerase

相关产品

Clinical Phase
生物活性分子 (2)
目录号 产品名 作用方式
纯度 Phase
HY-19720A Emixustat hydrochloride 99.29% Phase 3
HY-19720 Emixustat 98.00% Phase 3
Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-149325 RPE65-IN-1 ≥98.0% 否
HY-RS12151 RPE65 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22780 Rpe65 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS29294 Rpe65 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rpe65 NCBI NCBI:6121
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