2. Gene
  3. Polr2a - polymerase (RNA) II (DNA directed) polypeptide A Gene

Polr2a - polymerase (RNA) II (DNA directed) polypeptide A Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Rpb1; 220kDa; Rpo2-1

基因 ID: 20020 | 基因类型: protein coding

关于 Polr2a

功能概要

Enables core promoter sequence-specific DNA binding activity. Predicted to be involved in DNA-templated transcription, termination; positive regulation of RNA splicing; and transcription by RNA polymerase II. Located in euchromatin and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Orthologous to human POLR2A (RNA polymerase II subunit A). [provided by Alliance of Genome Resources, Apr 2022]

Polr2a 基因产物(1)

mRNA Protein Name
NM_001291068.1 NP_001277997.1 DNA-directed RNA polymerase II subunit RPB1
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
15601870 MGI
enables core promoter sequence-specific DNA binding IDA
IDA: 通过直接分析推断
22723415 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
8692929 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in euchromatin IDA
IDA: 通过直接分析推断
22723415 MGI
located in nucleus IDA
IDA: 通过直接分析推断
26346254 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

DNA-directed RNA polymerase II subunit RPB1

DNA-directed RNA polymerase II subunit A

DNA-directed RNA polymerase III largest subunit

RNA polymerase II 1

RNA polymerase II subunit B1

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-135646 Eleutheroside B1 Inhibitor 98.73% 否
HY-RS10842 POLR2A Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS19802 Polr2a Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS26298 Polr2a Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Polr2a NCBI NCBI:5430
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