1. Gene
  2. Rs1 - retinoschisis (X-linked, juvenile) 1 (human) Gene

Rs1 - retinoschisis (X-linked, juvenile) 1 (human) Gene

种属: Mus musculus

同用名: Rs1h; Xlrs1; tmgc1

基因 ID: 20147 | 基因类型: protein coding

关于 Rs1

功能概要

Enables phosphatidylinositol-3,4-bisphosphate binding activity and phospholipid binding activity. Acts upstream of or within adaptation of rhodopsin mediated signaling and retina layer formation. Located in extracellular region; neuron to neuron synapse; and photoreceptor inner segment. Is extrinsic component of plasma membrane. Used to study X-linked juvenile retinoschisis 1. Human ortholog(s) of this gene implicated in X-linked juvenile retinoschisis 1 and retinoschisis. Orthologous to human RS1 (retinoschisin 1). [provided by Alliance of Genome Resources, Apr 2022]

Rs1 基因产物(1)

mRNA Protein Name
NM_011302.3 NP_035432.3 retinoschisin precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
NOT enables phosphatidylcholine binding IDA
IDA: 通过直接分析推断
17325137 MGI
NOT enables phosphatidylethanolamine binding IDA
IDA: 通过直接分析推断
17325137 MGI
enables phosphatidylinositol-3,4,5-trisphosphate binding IDA
IDA: 通过直接分析推断
17325137 MGI
enables phosphatidylinositol-3,4-bisphosphate binding IDA
IDA: 通过直接分析推断
17325137 MGI
enables phosphatidylinositol-3,5-bisphosphate binding IDA
IDA: 通过直接分析推断
17325137 MGI
enables phosphatidylinositol-3-phosphate binding IDA
IDA: 通过直接分析推断
17325137 MGI
enables phosphatidylinositol-4,5-bisphosphate binding IDA
IDA: 通过直接分析推断
17325137 MGI
enables phosphatidylinositol-4-phosphate binding IDA
IDA: 通过直接分析推断
17325137 MGI
enables phosphatidylinositol-5-phosphate binding IDA
IDA: 通过直接分析推断
17325137 MGI
enables phosphatidylserine binding IDA
IDA: 通过直接分析推断
17325137 MGI
enables protein-containing complex binding IDA
IDA: 通过直接分析推断
17804407 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within retina layer formation IMP
IMP: 通过突变表型推断
11983912 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in cell surface IDA
IDA: 通过直接分析推断
17804407 MGI
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
17325137 MGI
located in extracellular region IDA
IDA: 通过直接分析推断
12853421 MGI
located in neuron to neuron synapse IDA
IDA: 通过直接分析推断
21196491 MGI
located in photoreceptor inner segment IDA
IDA: 通过直接分析推断
21196491 MGI
part of protein-containing complex IDA
IDA: 通过直接分析推断
17804407 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

retinoschisin

X-linked juvenile retinoschisis protein homolog

retinoschisis 1 homolog

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rs1 NCBI NCBI:6247
Macaca fascicularis Rs1 NCBI NCBI:107128453
Rattus norvegicus Rs1 NCBI NCBI:100125595