ADGRE1 - adhesion G protein-coupled receptor E1 Gene

中文名称：粘附 G 蛋白偶联受体 E1

种属: Homo sapiens

同用名: EMR1; TM7LN3

关于 ADGRE1

功能概要

该基因编码的蛋白质在其 C 末端具有类似于七个跨膜 G 蛋白偶联激素受体 (7TM 受体) 的结构域。编码蛋白的 N 端有六个 EGF 样模块，通过富含丝氨酸/苏氨酸的结构域与跨膜区段分开，这一特征让人联想到具有粘附特性的粘蛋白样、单跨度、整合膜糖蛋白。已为该基因发现编码不同亚型的多个可变剪接转录物变体。[RefSeq 提供，2012 年 1 月]

This gene encodes a protein that has a domain resembling seven transmembrane G protein-coupled hormone receptors (7TM receptors) at its C-terminus. The N-terminus of the encoded protein has six EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]