2. Gene
  3. Sema4c - sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C Gene

Sema4c - sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Semaf; Semai; sema I; Semacl1; M-Sema F

基因 ID: 20353 | 基因类型: protein coding

关于 Sema4c

功能概要

This gene encodes a member of the semaphorin family of proteins that have diverse functions in neuronal development, heart morphogenesis, vascular growth, tumor progression and immune cell regulation. Lack of the encoded protein in some mice causes exencephaly resulting in neonatal lethality. Mice that bypass exencephaly show no obvious behavioral defects but display distinct pigmentation defects. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2015]

Sema4c 基因产物(6)

mRNA Protein Name
NM_001126047.3 NP_001119519.1 semaphorin-4C precursor
NM_001304329.1 NP_001291258.1 semaphorin-4C precursor
NM_001304330.1 NP_001291259.1 semaphorin-4C precursor
NM_001126047.3 NP_001119519.1 semaphorin-4C precursor
NM_001304329.1 NP_001291258.1 semaphorin-4C precursor
NM_001304330.1 NP_001291259.1 semaphorin-4C precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
10318831 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cell migration in hindbrain IMP
IMP: 通过突变表型推断
21122816 MGI
involved in cerebellum development IMP
IMP: 通过突变表型推断
21122816 MGI
involved in muscle cell differentiation IMP
IMP: 通过突变表型推断
15811348 MGI
involved in neural tube closure IMP
IMP: 通过突变表型推断
21122816 MGI
involved in regulation of postsynapse assembly IDA
IDA: 通过直接分析推断
31444474 MGI
involved in regulation of postsynapse assembly IMP
IMP: 通过突变表型推断
31444474 MGI
involved in semaphorin-plexin signaling pathway IMP
IMP: 通过突变表型推断
21122816 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
11134026 MGI
is active in glutamatergic synapse IEP
IEP: 通过表达模式推断
11134026 MGI
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
31444474 MGI
located in postsynaptic density IDA
IDA: 通过直接分析推断
11134026 MGI
is active in postsynaptic density membrane IDA
IDA: 通过直接分析推断
11134026 MGI
is active in postsynaptic density membrane IEP
IEP: 通过表达模式推断
11134026 MGI
located in synaptic vesicle membrane IDA
IDA: 通过直接分析推断
11134026 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

semaphorin-4C

semaphorin I

semaphorin-C-like 1

重组 Sema4c 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71285 Semaphorin-4C/SEMA4C Protein, Mouse (HEK293, Fc) Q64151 (A21-G664） ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12659 SEMA4C Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19073 Sema4c Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25563 Sema4c Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sema4c NCBI NCBI:54910
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