2. Gene
  3. Sema6a - sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A Gene

Sema6a - sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: VIa; Semaq; Sema6A-1; A730020P05Rik

基因 ID: 20358 | 基因类型: protein coding

关于 Sema6a

功能概要

Enables identical protein binding activity; semaphorin receptor binding activity; and transmembrane signaling receptor activity. Involved in generation of neurons; positive regulation of neuron migration; and semaphorin-plexin signaling pathway. Acts upstream of or within cell surface receptor signaling pathway and centrosome localization. Is integral component of plasma membrane. Is expressed in several structures, including alimentary system; genitourinary system; limb mesenchyme; nervous system; and sensory organ. Orthologous to human SEMA6A (semaphorin 6A). [provided by Alliance of Genome Resources, Apr 2022]

Sema6a 基因产物(2)

mRNA Protein Name
NM_001311097.1 NP_001298026.1 semaphorin-6A isoform 2 precursor
NM_018744.2 NP_061214.2 semaphorin-6A isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
20877282 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
10993894 MGI
enables semaphorin receptor binding IGI
IGI: 通过遗传相互作用推断
18327254 MGI
enables semaphorin receptor binding IPI
IPI: 通过物理相互作用推断
15814794 MGI
enables transmembrane signaling receptor activity IMP
IMP: 通过突变表型推断
20877282 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in axon guidance IMP
IMP: 通过突变表型推断
16205717 MGI
acts upstream of or within cell surface receptor signaling pathway IDA
IDA: 通过直接分析推断
18327254 MGI
acts upstream of or within centrosome localization IMP
IMP: 通过突变表型推断
18327254 MGI
involved in neuron migration IMP
IMP: 通过突变表型推断
16205717 MGI
involved in positive regulation of neuron migration IMP
IMP: 通过突变表型推断
20877282 MGI
involved in semaphorin-plexin signaling pathway IMP
IMP: 通过突变表型推断
20877282 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in plasma membrane IDA
IDA: 通过直接分析推断
20877282 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

semaphorin-6A

Mutant line 997

sema Q

sema VIA

semaphorin Q

semaphorin VIA

semaphorin-6A-1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12665 SEMA6A Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21192 Sema6a Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27708 Sema6a Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sema6a NCBI NCBI:57556
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