2. Gene
  3. Sh2d1a - SH2 domain containing 1A Gene

Sh2d1a - SH2 domain containing 1A Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: SAP; Gm686

基因 ID: 20400 | 基因类型: protein coding

关于 Sh2d1a

功能概要

Acts upstream of or within humoral immune response and positive regulation of natural killer cell mediated cytotoxicity. Predicted to be located in cytoplasm. Is expressed in retina. Used to study X-linked lymphoproliferative syndrome 1. Human ortholog(s) of this gene implicated in X-linked lymphoproliferative syndrome 1. Orthologous to human SH2D1A (SH2 domain containing 1A). [provided by Alliance of Genome Resources, Apr 2022]

Sh2d1a 基因产物(4)

mRNA Protein Name
NM_001313688.1 NP_001300617.1 SH2 domain-containing protein 1A isoform 1
NM_001313689.1 NP_001300618.1 SH2 domain-containing protein 1A isoform 3
NM_001313691.1 NP_001300620.1 SH2 domain-containing protein 1A isoform 4
NM_011364.4 NP_035494.1 SH2 domain-containing protein 1A isoform 2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
10970095 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within humoral immune response IMP
IMP: 通过突变表型推断
12529646 MGI
acts upstream of natural killer cell mediated cytotoxicity IGI
IGI: 通过遗传相互作用推断
19648922 MGI
acts upstream of natural killer cell mediated cytotoxicity IMP
IMP: 通过突变表型推断
16127454 MGI
acts upstream of or within positive regulation of natural killer cell mediated cytotoxicity IGI
IGI: 通过遗传相互作用推断
19648922 MGI
acts upstream of or within positive regulation of natural killer cell mediated cytotoxicity IMP
IMP: 通过突变表型推断
16127454 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

SH2 domain-containing protein 1A

Duncan disease homolog

SH2 domain protein 1A

T-cell signal transduction molecule SAP

signaling lymphocytic activation molecule-associated protein

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12821 SH2D1A Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS21930 Sh2d1a Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS28446 Sh2d1a Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sh2d1a NCBI NCBI:4068
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