1. Gene
  2. Six6 - sine oculis-related homeobox 6 Gene

Six6 - sine oculis-related homeobox 6 Gene

种属: Mus musculus

同用名: Six9; Optx2

基因 ID: 20476 | 基因类型: protein coding

关于 Six6

功能概要

This gene encodes a homeobox protein that is similar to the Drosophila 'sine oculis' gene product. This gene is found in a cluster of related genes on chromosome 12 and is thought to be involved in eye development. The encoded transcription factor regulates early progenitor cell proliferation during mammalian retinogenesis and pituitary development. Mice lacking this gene exhibit abnormal development of the suprachiasmatic nucleus and circadian rhythms. [provided by RefSeq, Sep 2015]

Six6 基因产物(2)

mRNA Protein Name
NM_011384.5 NP_035514.1 homeobox protein SIX6
NM_011384.5 NP_035514.1 homeobox protein SIX6
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
18836447 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
12050133 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

homeobox protein SIX6

optic homeobox 2

sine oculis homeobox homolog 6

sine oculis-related homeobox 6 homolog

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Six6 NCBI NCBI:4990