Slc2a1 - solute carrier family 2 (facilitated glucose transporter), member 1 Gene

中文名称：溶质载体家族 2 (易化葡萄糖转运蛋白) ，成员 1

种属: Mus musculus

同用名: Glut1; Glut-1; M100200; Rgsc200

关于 Slc2a1

功能概要

该基因编码的蛋白可启动 D-葡萄糖跨膜转运蛋白活性和脱氢抗坏血酸跨膜转运蛋白活性。参与脱氢抗坏血酸转运和葡萄糖跨膜转运。在葡萄糖饥饿的细胞反应上游或细胞反应中起作用。位于几种细胞成分中，包括基底外侧质膜；雌性原核；和感光器内段。以多种结构表达，包括消化系统；中枢神经系统;早孕;泌尿生殖系统；和感觉器官。该基因的人类直系同源物与脑部疾病有关（多个）；碳水化合物代谢紊乱；脊髓脊膜膨出；肥胖;和 2 型糖尿病。与人类 SLC2A1（溶质载体家族 2 成员 1）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables D-glucose transmembrane transporter activity and dehydroascorbic acid transmembrane transporter activity. Involved in dehydroascorbic acid transport and glucose transmembrane transport. Acts upstream of or within cellular response to glucose starvation. Located in several cellular components, including basolateral plasma membrane; female pronucleus; and photoreceptor inner segment. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in brain disease (multiple); carbohydrate metabolic disorder; myelomeningocele; obesity; and type 2 diabetes mellitus. Orthologous to human SLC2A1 (solute carrier family 2 member 1). [provided by Alliance of Genome Resources, Apr 2022]