1. Gene
  2. Sumo3 - small ubiquitin-like modifier 3 Gene

Sumo3 - small ubiquitin-like modifier 3 Gene

种属: Mus musculus

同用名: SMT3A; SUMO-3; Smt3h1; D10Ertd345e; 2810014B19Rik

基因 ID: 20610 | 基因类型: protein coding

关于 Sumo3

功能概要

This gene encodes a member of the small ubiquitin-like modifier family. The encoded protein may regulate a variety of proteins in many pathways via a post-translational modification, known as SUMOylation. This activity may play a role in a wide variety of cellular processes, including nuclear transport, DNA replication and repair, Mitosis, transcriptional regulation, and signal transduction. Disruption of some of these processes has been associated with cerebral ischemia, neural dysfunction, and heart disease. A pseudogene of this gene has been defined on the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]

Sumo3 基因产物(4)

mRNA Protein Name
NM_001301671.1 NP_001288600.1 small ubiquitin-related modifier 3 isoform 2
NM_001301672.1 NP_001288601.1 small ubiquitin-related modifier 3 isoform 3
NM_001301673.1 NP_001288602.1 small ubiquitin-related modifier 3 isoform 4
NM_019929.4 NP_064313.1 small ubiquitin-related modifier 3 isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables SUMO transferase activity IDA
IDA: 通过直接分析推断
15767674 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within positive regulation of ubiquitin-dependent protein catabolic process IDA
IDA: 通过直接分析推断
18644859 MGI
acts upstream of or within protein localization to nucleus IDA
IDA: 通过直接分析推断
18644859 MGI
acts upstream of or within protein sumoylation IDA
IDA: 通过直接分析推断
15767674 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
31749687 MGI
located in nuclear body IDA
IDA: 通过直接分析推断
18644859 MGI
is active in postsynaptic cytosol IDA
IDA: 通过直接分析推断
31749687 MGI
is active in presynaptic cytosol IDA
IDA: 通过直接分析推断
31749687 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

small ubiquitin-related modifier 3

SMT3 suppressor of mif two 3 homolog 3

ubiquitin-like protein SMT3A

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sumo3 NCBI NCBI:6612