2. Gene
  3. Snai1 - snail family zinc finger 1 Gene

Snai1 - snail family zinc finger 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Sna; Sna1; Snail; Snail1

基因 ID: 20613 | 基因类型: protein coding

关于 Snai1

功能概要

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including heart development; positive regulation of epithelial to mesenchymal transition; and regulation of transcription, DNA-templated. Acts upstream of or within several processes, including animal organ development; left/right pattern formation; and negative regulation of cell differentiation involved in embryonic placenta development. Located in cytoplasm; nucleus; and pericentric heterochromatin. Is expressed in several structures, including central nervous system; early conceptus; embryo mesenchyme; genitourinary system; and sensory organ. Used to study dilated cardiomyopathy and skin Cancer. Orthologous to human SNAI1 (snail family transcriptional repressor 1). [provided by Alliance of Genome Resources, Apr 2022]

Snai1 基因产物(1)

mRNA Protein Name
NM_011427.3 NP_035557.1 zinc finger protein SNAI1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
12917416 MGI
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
12917416 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
18331720 MGI
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
9676199 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in Notch signaling pathway IGI
IGI: 通过遗传相互作用推断
20890042 MGI
acts upstream of or within cartilage morphogenesis IGI
IGI: 通过遗传相互作用推断
17376812 MGI
acts upstream of or within epithelial cell migration IGI
IGI: 通过遗传相互作用推断
17376812 MGI
involved in epithelial to mesenchymal transition IDA
IDA: 通过直接分析推断
10655586 MGI
involved in epithelial to mesenchymal transition IMP
IMP: 通过突变表型推断
11689706 MGI
involved in epithelial to mesenchymal transition involved in endocardial cushion formation IGI
IGI: 通过遗传相互作用推断
18663143 MGI
acts upstream of or within hair follicle morphogenesis IDA
IDA: 通过直接分析推断
15630473 MGI
involved in heterochromatin organization IMP
IMP: 通过突变表型推断
24239292 MGI
acts upstream of or within left/right pattern formation IMP
IMP: 通过突变表型推断
16801545 MGI
acts upstream of or within mesoderm development IMP
IMP: 通过突变表型推断
16801545 MGI
involved in mesoderm formation IMP
IMP: 通过突变表型推断
11689706 MGI
involved in negative regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
10655586 MGI
acts upstream of or within negative regulation of cell differentiation involved in embryonic placenta development IDA
IDA: 通过直接分析推断
9676199 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
9676199 MGI
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
12917416 MGI
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
10655586 MGI
involved in positive regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
12832491 MGI
involved in positive regulation of cell migration IMP
IMP: 通过突变表型推断
20890042 MGI
involved in positive regulation of epithelial to mesenchymal transition IMP
IMP: 通过突变表型推断
20890042 MGI
acts upstream of or within regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
9676199 MGI
acts upstream of or within roof of mouth development IGI
IGI: 通过遗传相互作用推断
17376812 MGI
acts upstream of or within trophoblast giant cell differentiation IDA
IDA: 通过直接分析推断
9676199 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
12832491 MGI
located in nucleus IDA
IDA: 通过直接分析推断
12832491 MGI
located in pericentric heterochromatin IDA
IDA: 通过直接分析推断
24239292 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

zinc finger protein SNAI1

snail homolog 1

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-10456 TAK-715 Inhibitor 99.76% Phase 2
Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13470 SNAI1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-P5291 CPF-7 / 否
HY-RS19742 Snai1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26238 Snai1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Snai1 NCBI NCBI:6615
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