1. Gene
  2. LVRN - laeverin Gene

LVRN - laeverin Gene

中文名称:紫菜素

种属: Homo sapiens

同用名: APQ; AQPEP; TAQPEP

基因 ID: 206338 | 基因类型: protein coding

关于 LVRN

Cytogenetic location: 5q23.1 Genomic coordinates (GRCh38): 5:115,962,475-116,027,606 (from NCBI)

This gene has 9 transcripts (splice variants), 224 orthologues and 11 paralogues. Biased expression in fat (RPKM 11.6), placenta (RPKM 10.8) and 1 other tissue.

功能概要

预测启用金属氨基肽酶活性;肽结合活性;和锌离子结合活性。预计参与多个过程,包括肽分解代谢过程;蛋白水解;和调节血压。预计是膜的组成部分。预计在细胞质和质膜中有活性。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable metalloaminopeptidase activity; peptide binding activity; and zinc ion binding activity. Predicted to be involved in several processes, including peptide catabolic process; proteolysis; and regulation of blood pressure. Predicted to be integral component of membrane. Predicted to be active in cytoplasm and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

LVRN 基因产物(1)

mRNA Protein Name
NM_173800.5 NP_776161.3 aminopeptidase Q
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32814053 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

LVRN 蛋白结构

Peptidase_M1

Peptidase_M1: Peptidase family M1 domain (97 - 506)

ERAP1_C

ERAP1_C: ERAP1-like C-terminal domain (647 - 955)

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  • 990 a.a.
蛋白主名 其他名称

aminopeptidase Q

AP-Q

关联疾病

疾病名称 别名
Lacrimal Gland Carcinoma

Lacrimal Gland Cancer

Carcinoma Of The Lacrimal Gland

Malignant Neoplasm Of Lacrimal Gland

Malignant Tumour Of Lacrimal Gland

Neoplasm Of Lacrimal Gland

Tumor Of The Lacrimal Gland

Malignant Tumor Of Lacrimal Gland

Lacrimal Gland Adenoid Cystic Carcinoma

Adenoid Cystic Carcinoma Of Lacrimal Gland

Lacrimal Gland Adenocarcinoma

Adenocarcinoma Of Lacrimal Gland

Lacrimal System Cancer

Neoplasm Of Lacrimal System

Lacrimal System Neoplasm

Tumor Of The Lacrimal System

Astigmatism
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus LVRN MGD MGI:1921824
Rattus norvegicus LVRN RGD RGD:1562779
Macaca mulatta LVRN VGNC VGNC:74372
Felis catus LVRN VGNC VGNC:102247
Bos taurus LVRN VGNC VGNC:31086
Canis familiaris LVRN VGNC VGNC:42870