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  3. Spink1 - serine peptidase inhibitor, Kazal type 1 Gene

Spink1 - serine peptidase inhibitor, Kazal type 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: p12; Spink3

基因 ID: 20730 | 基因类型: protein coding

关于 Spink1

功能概要

Enables serine-type endopeptidase inhibitor activity. Acts upstream of or within several processes, including negative regulation of cellular protein metabolic process; negative regulation of nitric oxide mediated signal transduction; and regulation of calcium ion transport. Located in extracellular space. Is expressed in embryo ectoderm; embryo endoderm; genitourinary system; gut; and yolk sac. Human ortholog(s) of this gene implicated in pancreatitis. Orthologous to human SPINK1 (serine peptidase inhibitor Kazal type 1). [provided by Alliance of Genome Resources, Apr 2022]

Spink1 基因产物(1)

mRNA Protein Name
NM_009258.5 NP_033284.1 serine protease inhibitor Kazal-type 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables peptidase inhibitor activity IDA
IDA: 通过直接分析推断
3428272 MGI
enables serine-type endopeptidase inhibitor activity IDA
IDA: 通过直接分析推断
18715980 MGI
enables serine-type endopeptidase inhibitor activity IMP
IMP: 通过突变表型推断
20110462 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within negative regulation of calcium ion import IDA
IDA: 通过直接分析推断
2430282 MGI
acts upstream of or within negative regulation of nitric oxide mediated signal transduction IDA
IDA: 通过直接分析推断
22228629 MGI
acts upstream of or within negative regulation of peptidase activity IDA
IDA: 通过直接分析推断
3428272 MGI
acts upstream of or within negative regulation of peptidyl-tyrosine phosphorylation IDA
IDA: 通过直接分析推断
22228629 MGI
acts upstream of or within negative regulation of serine-type endopeptidase activity IDA
IDA: 通过直接分析推断
22228629 MGI
acts upstream of or within negative regulation of serine-type endopeptidase activity IMP
IMP: 通过突变表型推断
20110462 MGI
acts upstream of nitric oxide mediated signal transduction IDA
IDA: 通过直接分析推断
22228629 MGI
acts upstream of peptidyl-tyrosine phosphorylation IDA
IDA: 通过直接分析推断
22228629 MGI
acts upstream of or within regulation of acrosome reaction IDA
IDA: 通过直接分析推断
22228629 MGI
acts upstream of or within regulation of store-operated calcium entry IDA
IDA: 通过直接分析推断
22228629 MGI
acts upstream of or within sperm capacitation IDA
IDA: 通过直接分析推断
22228629 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
18715980 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

serine protease inhibitor Kazal-type 1

prostatic secretory glycoprotein

serine peptidase inhibitor, Kazal type 3

serine protease inhibitor Kazal-type 3

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13679 SPINK1 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS19269 Spink1 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS25758 Spink1 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Spink1 NCBI NCBI:6690
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