1. Gene
  2. Hectd1 - HECT domain E3 ubiquitin protein ligase 1 Gene

Hectd1 - HECT domain E3 ubiquitin protein ligase 1 Gene

种属: Mus musculus

同用名: opm; b2b327Clo; A630086P08Rik

基因 ID: 207304 | 基因类型: protein coding

关于 Hectd1

功能概要

Enables ubiquitin protein Ligase activity. Acts upstream of or within several processes, including animal organ development; negative regulation of protein localization to plasma membrane; and protein ubiquitination. Is expressed in several structures, including extraembryonic component; genitourinary system; heart; hemolymphoid system gland; and lung. Orthologous to human HECTD1 (HECT domain E3 ubiquitin protein Ligase 1). [provided by Alliance of Genome Resources, Apr 2022]

Hectd1 基因产物(8)

mRNA Protein Name
NM_001405181.1 NP_001392110.1 E3 ubiquitin-protein ligase HECTD1 isoform 2
NM_001405182.1 NP_001392111.1 E3 ubiquitin-protein ligase HECTD1 isoform 3
NM_001405183.1 NP_001392112.1 E3 ubiquitin-protein ligase HECTD1 isoform 4
NM_001405184.1 NP_001392113.1 E3 ubiquitin-protein ligase HECTD1 isoform 5
NM_001405185.1 NP_001392114.1 E3 ubiquitin-protein ligase HECTD1 isoform 6
NM_001405186.1 NP_001392115.1 E3 ubiquitin-protein ligase HECTD1 isoform 7
NM_001405187.1 NP_001392116.1 E3 ubiquitin-protein ligase HECTD1 isoform 8
NM_144788.3 NP_659037.2 E3 ubiquitin-protein ligase HECTD1 isoform 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
22431752 MGI
enables ubiquitin protein ligase activity IDA
IDA: 通过直接分析推断
22431752 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within aorta development IMP
IMP: 通过突变表型推断
25807483 MGI
acts upstream of or within embryonic placenta development IMP
IMP: 通过突变表型推断
24855001 MGI
acts upstream of or within heart valve development IMP
IMP: 通过突变表型推断
25807483 MGI
acts upstream of or within natural killer cell differentiation IMP
IMP: 通过突变表型推断
24855001 MGI
acts upstream of or within negative regulation of protein localization to plasma membrane IMP
IMP: 通过突变表型推断
22431752 MGI
acts upstream of or within neural tube closure IMP
IMP: 通过突变表型推断
9636176 MGI
involved in neural tube closure IMP
IMP: 通过突变表型推断
17442300 MGI
acts upstream of or within protein K63-linked ubiquitination IDA
IDA: 通过直接分析推断
22431752 MGI
acts upstream of or within protein K63-linked ubiquitination IMP
IMP: 通过突变表型推断
22431752 MGI
acts upstream of or within protein autoubiquitination IMP
IMP: 通过突变表型推断
22431752 MGI
acts upstream of protein localization to plasma membrane IMP
IMP: 通过突变表型推断
22431752 MGI
acts upstream of or within spongiotrophoblast differentiation IMP
IMP: 通过突变表型推断
24855001 MGI
acts upstream of or within trophoblast giant cell differentiation IMP
IMP: 通过突变表型推断
24855001 MGI
acts upstream of or within ventricular septum development IMP
IMP: 通过突变表型推断
25807483 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

E3 ubiquitin-protein ligase HECTD1

HECT domain containing 1

HECT domain-containing protein 1

HECT-type E3 ubiquitin transferase HECTD1

protein open mind

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hectd1 NCBI NCBI:25831