1. Gene
  2. ERV3-1 - endogenous retrovirus group 3 member 1, envelope Gene

ERV3-1 - endogenous retrovirus group 3 member 1, envelope Gene

中文名称:内源性逆转录病毒第 3 组成员 1,包膜

种属: Homo sapiens

同用名: ERV3; ERVR; envR; ERV-R; HERVR; HERV-R

基因 ID: 2086 | 基因类型: protein coding

关于 ERV3-1

Cytogenetic location: 7q11.21 Genomic coordinates (GRCh38): 7:64,990,356-65,006,687 (from NCBI)

This gene has 3 transcripts (splice variants), 136 orthologues and 5 paralogues. Ubiquitous expression in adrenal (RPKM 19.4), fat (RPKM 15.6) and 23 other tissues.

功能概要

该基因包含来自内源性逆转录病毒的序列,因此与基因组中的多个其他基因座相似。该位点的转录本编码一种具有预测信号肽且与 Env 多聚蛋白相似的保守蛋白。这种蛋白质在结直肠癌和其他癌症中过度表达。[RefSeq 提供,2017 年 1 月]

This gene contains sequence derived from endogenous retrovirus, and is therefore similar to multiple Other loci in the genome. Transcripts at this locus encode a conserved protein with a predicted signal peptide and similarity to the Env polyprotein. This protein is overexpressed in colorectal and Other cancers. [provided by RefSeq, Jan 2017]

ERV3-1 基因产物(2)

mRNA Protein Name
NM_001007253.4 NP_001007254.2 endogenous retrovirus group 3 member 1 Env polyprotein precursor
NM_001396062.1 NP_001382991.1 endogenous retrovirus group 3 member 1 Env polyprotein precursor
蛋白主名 其他名称

endogenous retrovirus group 3 member 1 Env polyprotein

ERV-R envelope protein

关联疾病

疾病名称 别名
Choriocarcinoma

Chorioepithelioma

Heart Block, Congenital

Congenital Heart Block

Heart Block Congenital

Congenital Atrioventricular Block

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma