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  2. Bhlhe40 - basic helix-loop-helix family, member e40 Gene

Bhlhe40 - basic helix-loop-helix family, member e40 Gene

种属: Mus musculus

同用名: CR8; Dec1; Bhlhb2; Clast5; Sharp2; Stra13; Stra14; C130042M06Rik

基因 ID: 20893 | 基因类型: protein coding

关于 Bhlhe40

功能概要

This gene encodes a basic helix-loop-helix protein expressed in various tissues. The encoded protein can interact with Arntl or compete for E-box binding sites in the promoter of Per1 and repress Clock/Arntl's transactivation of Per1. This gene is believed to be involved in the control of circadian rhythm and cell differentiation. [provided by RefSeq, Feb 2014]

Bhlhe40 基因产物(1)

mRNA Protein Name
NM_011498.4 NP_035628.1 class E basic helix-loop-helix protein 40
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
12297495 MGI
enables DNA-binding transcription factor activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
15147242 MGI
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
15147242 MGI
enables E-box binding IDA
IDA: 通过直接分析推断
12397359 MGI
enables MRF binding IDA
IDA: 通过直接分析推断
17487425 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
15147242 MGI
enables RNA polymerase II-specific DNA-binding transcription factor binding IDA
IDA: 通过直接分析推断
17487425 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
12297495 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in circadian regulation of gene expression IMP
IMP: 通过突变表型推断
18411297 MGI
involved in circadian rhythm IEP
IEP: 通过表达模式推断
19786558 MGI
involved in entrainment of circadian clock by photoperiod IMP
IMP: 通过突变表型推断
18411297 MGI
acts upstream of or within negative regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
12297495 MGI
involved in negative regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
30012868 MGI
involved in regulation of circadian rhythm IMP
IMP: 通过突变表型推断
30012868 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
12297495 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

class E basic helix-loop-helix protein 40

E47 interaction protein 1

basic helix-loop-helix domain containing, class B2

class B basic helix-loop-helix protein 2

cytokine response gene 8

differentially expressed in chondrocytes protein 1

eip1 (E47 interaction protein 1)

stimulated by retinoic

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Bhlhe40 NCBI NCBI:8553