2. Gene
  3. Syp - synaptophysin Gene

Syp - synaptophysin Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Syn; p38; A230093K24Rik

基因 ID: 20977 | 基因类型: protein coding

关于 Syp

功能概要

Enables SH2 domain binding activity and identical protein binding activity. Involved in modulation of chemical synaptic transmission and synaptic vesicle endocytosis. Acts upstream of or within cellular response to organic substance. Located in several cellular components, including neuromuscular junction; presynaptic membrane; and synaptic vesicle membrane. Is active in Schaffer collateral - CA1 synapse. Is expressed in diaphragm; gut; nervous system; sensory organ; and skeletal muscle. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 96. Orthologous to human SYP (synaptophysin). [provided by Alliance of Genome Resources, Apr 2022]

Syp 基因产物(1)

mRNA Protein Name
NM_009305.2 NP_033331.2 synaptophysin
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables SH2 domain binding IDA
IDA: 通过直接分析推断
18706977 MGI
enables identical protein binding IPI
IPI: 通过物理相互作用推断
18706977 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
18706977 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in modulation of chemical synaptic transmission IDA
IDA: 通过直接分析推断
10595519 MGI
involved in modulation of chemical synaptic transmission IMP
IMP: 通过突变表型推断
10595519 MGI
involved in regulation of long-term neuronal synaptic plasticity IMP
IMP: 通过突变表型推断
10595519 MGI
involved in regulation of short-term neuronal synaptic plasticity IMP
IMP: 通过突变表型推断
10595519 MGI
involved in regulation of synaptic vesicle priming IDA
IDA: 通过直接分析推断
31090538 MGI
involved in regulation of synaptic vesicle priming IMP
IMP: 通过突变表型推断
31090538 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in Schaffer collateral - CA1 synapse IDA
IDA: 通过直接分析推断
10595519 MGI
is active in Schaffer collateral - CA1 synapse IMP
IMP: 通过突变表型推断
10595519 MGI
located in excitatory synapse IDA
IDA: 通过直接分析推断
16980967 MGI
located in membrane IDA
IDA: 通过直接分析推断
15748150 MGI
located in neuromuscular junction IDA
IDA: 通过直接分析推断
20826656 MGI
located in neuron projection IDA
IDA: 通过直接分析推断
21307259 MGI
located in neuron projection IMP
IMP: 通过突变表型推断
21664258 MGI
located in neuron projection terminus IDA
IDA: 通过直接分析推断
12074840 MGI
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
17046993 MGI
located in presynapse IDA
IDA: 通过直接分析推断
31787876 MGI
is active in presynaptic active zone IDA
IDA: 通过直接分析推断
21664258 MGI
located in presynaptic membrane IDA
IDA: 通过直接分析推断
15328414 MGI
located in synapse IDA
IDA: 通过直接分析推断
10712642 MGI
located in synaptic vesicle IDA
IDA: 通过直接分析推断
9364068 MGI
located in synaptic vesicle membrane IDA
IDA: 通过直接分析推断
12805290 MGI
located in terminal bouton IDA
IDA: 通过直接分析推断
20203623 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

synaptophysin

BM89 antigen

Syp I

major synaptic vesicle protein p38

相关产品

Pre-clinical Phase
生物活性分子 (8)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-100693 SYP-5 Inhibitor 99.21% 否
HY-136356 Triclopyricarb Inhibitor / 否
HY-136915 Pyrisoxazole Inhibitor / 否
HY-RS14102 SYP Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16733 Ptpn11 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20686 Syp Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27197 Syp Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-17521 Flumorph Inhibitor 99.57% 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Syp NCBI NCBI:6855
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