2. Gene
  3. Mettl14 - methyltransferase like 14 Gene

Mettl14 - methyltransferase like 14 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: mKIAA1627; G430022H21Rik

基因 ID: 210529 | 基因类型: protein coding

关于 Mettl14

功能概要

Enables mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity. Involved in several processes, including forebrain radial glial cell differentiation; mRNA destabilization; and mRNA metabolic process. Located in nucleus. Part of RNA N6-methyladenosine methyltransferase complex. Orthologous to human METTL14 (methyltransferase 14, N6-adenosine-methyltransferase subunit). [provided by Alliance of Genome Resources, Apr 2022]

Mettl14 基因产物(1)

mRNA Protein Name
NM_201638.2 NP_964000.2 N6-adenosine-methyltransferase non-catalytic subunit
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables mRNA m(6)A methyltransferase activity IDA
IDA: 通过直接分析推断
24394384 MGI
enables mRNA m(6)A methyltransferase activity IMP
IMP: 通过突变表型推断
31340148 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
24394384 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in RNA methylation IMP
IMP: 通过突变表型推断
28914256 MGI
involved in forebrain radial glial cell differentiation IMP
IMP: 通过突变表型推断
28965759 MGI
involved in gliogenesis IMP
IMP: 通过突变表型推断
28965759 MGI
involved in mRNA destabilization IMP
IMP: 通过突变表型推断
24394384 MGI
involved in mRNA modification IMP
IMP: 通过突变表型推断
31340148 MGI
involved in mRNA processing IDA
IDA: 通过直接分析推断
24394384 MGI
involved in mRNA stabilization IDA
IDA: 通过直接分析推断
29290617 MGI
acts upstream of negative regulation of hematopoietic progenitor cell differentiation IMP
IMP: 通过突变表型推断
29290617 MGI
acts upstream of positive regulation of translation IDA
IDA: 通过直接分析推断
29290617 MGI
involved in regulation of neuron differentiation IMP
IMP: 通过突变表型推断
31340148 MGI
involved in spermatogenesis IMP
IMP: 通过突变表型推断
28914256 MGI
involved in stem cell population maintenance IMP
IMP: 通过突变表型推断
24394384 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of RNA N6-methyladenosine methyltransferase complex IDA
IDA: 通过直接分析推断
29290617 MGI
is active in nucleus IDA
IDA: 通过直接分析推断
24394384 MGI
located in nucleus IDA
IDA: 通过直接分析推断
28914256 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

N6-adenosine-methyltransferase non-catalytic subunit

N6-adenosine-methyltransferase subunit METTL14

methyltransferase-like protein 14

snoRNA MBII-84

相关产品

Pre-clinical Phase
生物活性分子 (16)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-19528 SAH 99.90% 否
HY-160415A WD6305 TFA 99.81% 否
HY-19528S SAH-d4 ≥99.0% 否
HY-N0353 Curdione Inhibitor 99.92% 否
HY-153625 STM2120 Inhibitor 99.92% 否
HY-P10387 RSM3 95.73% 否
HY-RS08355 METTL14 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-P10387A RSM3 TFA 98.83% 否
HY-151926 Antiviral agent 24 Inhibitor 99.63% 否
HY-19528S2 SAH-13C10 99.90% 否
HY-RS16861 Mettl14 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-151924 Antiviral agent 23 Inhibitor / 否
HY-160415 WD6305 / 否
HY-162282 PROTAC METTL3-14 degrader 1 Degrader / 否
HY-W125425 METTL3 activator-1 free base Activator / 否
HY-RS23302 Mettl14 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mettl14 NCBI NCBI:57721
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