2. Gene
  3. Mkx - mohawk homeobox Gene

Mkx - mohawk homeobox Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Irxl1; 9430023B20Rik

基因 ID: 210719 | 基因类型: protein coding

关于 Mkx

功能概要

Enables DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including Collagen fibril organization; regulation of gene expression; and tendon development. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Is expressed in several structures, including embryo mesenchyme; genitourinary system; limb; limb bud; and sensory organ. Orthologous to human MKX (mohawk homeobox). [provided by Alliance of Genome Resources, Apr 2022]

Mkx 基因产物(1)

mRNA Protein Name
NM_177595.4 NP_808263.2 homeobox protein Mohawk
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
22923612 MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific IMP
IMP: 通过突变表型推断
22923612 MGI
enables DNA-binding transcription factor activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
19235719 MGI
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
22923612 MGI
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IMP
IMP: 通过突变表型推断
22923612 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
22923612 MGI
enables RNA polymerase II-specific DNA-binding transcription factor binding IPI
IPI: 通过物理相互作用推断
19235719 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
19235719 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within collagen fibril organization IMP
IMP: 通过突变表型推断
20696843 MGI
involved in muscle organ development IEP
IEP: 通过表达模式推断
16408284 MGI
acts upstream of or within negative regulation of myoblast differentiation IDA
IDA: 通过直接分析推断
19235719 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
19235719 MGI
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
22923612 MGI
acts upstream of or within positive regulation of collagen biosynthetic process IMP
IMP: 通过突变表型推断
20498044 MGI
acts upstream of or within positive regulation of gene expression IMP
IMP: 通过突变表型推断
20696843 MGI
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
22923612 MGI
acts upstream of or within regulation of gene expression IMP
IMP: 通过突变表型推断
20498044 MGI
acts upstream of or within tendon cell differentiation IMP
IMP: 通过突变表型推断
20696843 MGI
acts upstream of or within tendon formation IMP
IMP: 通过突变表型推断
20498044 MGI
acts upstream of or within tendon sheath development IMP
IMP: 通过突变表型推断
20696843 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

homeobox protein Mohawk

iroquois homeobox protein-like 1

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08483 MKX Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22081 Mkx Mouse Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mkx NCBI NCBI:283078
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