2. Gene
  3. EVX1 - even-skipped homeobox 1 Gene

EVX1 - even-skipped homeobox 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：偶数跳过的同源框 1

种属: Homo sapiens

同用名: EVX-1

基因 ID: 2128 | 基因类型: protein coding

关于 EVX1

Cytogenetic location: 7p15.2 Genomic coordinates (GRCh38): 7:27,242,802-27,247,830 (from NCBI)

This gene has 4 transcripts (splice variants), 195 orthologues and 50 paralogues. Biased expression in prostate (RPKM 2.2), adrenal (RPKM 1.7) and 3 other tissues.

功能概要

该基因编码 even-skipped 同源框家族的一个成员，其特征是存在与配对规则类的 Drosophila even-skipped (eve) 分割基因密切相关的同源域。编码的蛋白质可能在胚胎发生过程中作为转录抑制因子发挥重要作用。[RefSeq 提供，2008 年 7 月]

This gene encodes a member of the even-skipped homeobox family characterized by the presence of a homeodomain closely related to the Drosophila even-skipped (eve) segmentation gene of the pair-rule class. The encoded protein may play an important role as a transcriptional repressor during embryogenesis. [provided by RefSeq, Jul 2008]

EVX1 基因产物(3)

mRNA Protein Name
NM_001304519.2 NP_001291448.1 homeobox even-skipped homolog protein 1 isoform 2
NM_001304520.2 NP_001291449.1 homeobox even-skipped homolog protein 1 isoform 2
NM_001989.5 NP_001980.1 homeobox even-skipped homolog protein 1 isoform 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables sequence-specific double-stranded DNA binding IDA
IDA: 通过直接分析推断
28473536 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

EVX1 蛋白结构

Homeobox

Homeobox: Homeobox domain (184 - 240)

  • 0
  • 100
  • 200
  • 300
  • 407 a.a.
蛋白主名 其他名称

homeobox even-skipped homolog protein 1

eve, even-skipped homeo box homolog 1

关联疾病

疾病名称 别名
Hand-Foot-Genital Syndrome

Hand-Foot-Uterus Syndrome

Hfgs

Hfg Syndrome

Hfu Syndrome

HFG

Hfu

Hand Foot Uterus Syndrome

Hand Foot Genital Syndrome
Preaxial Deficiency, Postaxial Polydactyly, And Hypospadias

Guttmacher Syndrome

Preaxial Deficiency, Postaxial Polydactyly And Hypospadias

Autosomal Dominant Preaxial Deficiency, Postaxial Polydactyly, And Hypospadias

Preaxial Deficiency-Postaxial Polydactyly-Hypospadias Syndrome

GUTTS
Cervical Incompetence

Uterine Cervical Incompetence
Congenital Central Hypoventilation Syndrome

Cchs

Haddad Syndrome

Ondine Curse

Ondine Syndrome

Congenital Central Hypoventilation

Congenital Central Alveolar Hypoventilation Syndrome

Congenital Failure Of Autonomic Control

Ondine'S Curse

Primary Alveolar Hypoventilation

Ondine-Hirschsprung Disease

Central Congenital Hypoventilation Syndrome

Congenital Ondine Curse

Idiopathic Congenital Central Alveolar Hypoventilation

Congenital Central Alveolar Hypoventilation-Hirschsprung Disease Syndrome

Ondine-Hirschsprung Syndrome
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04579 EVX1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20730 Evx1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27242 Evx1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus EVX1 VGNC VGNC:28637
Canis familiaris EVX1 VGNC VGNC:40506
Rattus norvegicus EVX1 RGD RGD:11434685
Felis catus EVX1 VGNC VGNC:61992
Macaca mulatta EVX1 VGNC VGNC:108403
Mus musculus EVX1 MGD MGI:95461
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