2. Gene
  3. Tbx3 - T-box 3 Gene

Tbx3 - T-box 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: D5Ertd189e

基因 ID: 21386 | 基因类型: protein coding

关于 Tbx3

功能概要

Enables DNA-binding transcription factor activity and RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in atrioventricular canal morphogenesis. Acts upstream of or within several processes, including animal organ development; embryonic limb morphogenesis; and regulation of transcription, DNA-templated. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and sensory organ. Used to study ulnar-mammary syndrome. Human ortholog(s) of this gene implicated in ulnar-mammary syndrome. Orthologous to human TBX3 (T-box transcription factor 3). [provided by Alliance of Genome Resources, Apr 2022]

Tbx3 基因产物(2)

mRNA Protein Name
NM_011535.3 NP_035665.2 T-box transcription factor TBX3 isoform 1
NM_198052.2 NP_932169.1 T-box transcription factor TBX3 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
17473172 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
27720610 MGI
enables RNA polymerase II-specific DNA-binding transcription factor binding IPI
IPI: 通过物理相互作用推断
22164283 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
27046536 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of DNA-templated transcription IMP
IMP: 通过突变表型推断
17473172 MGI
acts upstream of or within atrioventricular bundle cell differentiation IMP
IMP: 通过突变表型推断
18467625 MGI
involved in atrioventricular canal development IGI
IGI: 通过遗传相互作用推断
22130515 MGI
involved in atrioventricular canal morphogenesis IGI
IGI: 通过遗传相互作用推断
22130515 MGI
acts upstream of or within blood vessel development IMP
IMP: 通过突变表型推断
12668638 MGI
acts upstream of or within branching involved in mammary gland duct morphogenesis IMP
IMP: 通过突变表型推断
16222716 MGI
acts upstream of or within cardiac muscle cell differentiation IMP
IMP: 通过突变表型推断
17234970 MGI
acts upstream of or within cardiac muscle cell fate commitment IMP
IMP: 通过突变表型推断
18467625 MGI
acts upstream of or within cellular senescence IDA
IDA: 通过直接分析推断
11748239 MGI
acts upstream of or within embryonic digit morphogenesis IMP
IMP: 通过突变表型推断
23844108 MGI
involved in embryonic digit morphogenesis IMP
IMP: 通过突变表型推断
27046536 MGI
acts upstream of or within embryonic heart tube development IMP
IMP: 通过突变表型推断
23844108 MGI
acts upstream of or within embryonic hindlimb morphogenesis IMP
IMP: 通过突变表型推断
23844108 MGI
acts upstream of or within heart looping IMP
IMP: 通过突变表型推断
17460765 MGI
acts upstream of or within heart morphogenesis IMP
IMP: 通过突变表型推断
17473172 MGI
acts upstream of hepatoblast differentiation IMP
IMP: 通过突变表型推断
18356246 MGI
acts upstream of or within in utero embryonic development IMP
IMP: 通过突变表型推断
17473172 MGI
involved in inner ear morphogenesis IGI
IGI: 通过遗传相互作用推断
33795231 MGI
acts upstream of or within limb morphogenesis IMP
IMP: 通过突变表型推断
12668638 MGI
involved in limb morphogenesis IMP
IMP: 通过突变表型推断
27046536 MGI
acts upstream of or within limbic system development IMP
IMP: 通过突变表型推断
17473172 MGI
acts upstream of or within mammary gland development IMP
IMP: 通过突变表型推断
12668638 MGI
acts upstream of or within mammary placode formation IDA
IDA: 通过直接分析推断
17071745 MGI
acts upstream of or within mammary placode formation IGI
IGI: 通过遗传相互作用推断
16222716 MGI
acts upstream of or within negative regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
11748239 MGI
acts upstream of or within negative regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
17473172 MGI
acts upstream of or within negative regulation of epithelial cell differentiation IMP
IMP: 通过突变表型推断
18356246 MGI
acts upstream of or within negative regulation of stem cell differentiation IMP
IMP: 通过突变表型推断
18356246 MGI
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
27720610 MGI
acts upstream of or within outflow tract morphogenesis IMP
IMP: 通过突变表型推断
18723448 MGI
acts upstream of or within positive regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
17473172 MGI
acts upstream of or within positive regulation of stem cell proliferation IMP
IMP: 通过突变表型推断
18356246 MGI
acts upstream of or within regulation of cell population proliferation IMP
IMP: 通过突变表型推断
17460765 MGI
involved in regulation of protein complex stability IMP
IMP: 通过突变表型推断
27046536 MGI
involved in regulation of protein stability IMP
IMP: 通过突变表型推断
27046536 MGI
acts upstream of or within roof of mouth development IGI
IGI: 通过遗传相互作用推断
19769959 MGI
involved in semicircular canal morphogenesis IMP
IMP: 通过突变表型推断
33795231 MGI
acts upstream of or within sinoatrial node cell development IMP
IMP: 通过突变表型推断
19096026 MGI
acts upstream of or within smooth muscle cell differentiation IGI
IGI: 通过遗传相互作用推断
30478225 MGI
acts upstream of or within specification of animal organ position IDA
IDA: 通过直接分析推断
17071745 MGI
acts upstream of or within stem cell population maintenance IMP
IMP: 通过突变表型推断
18356246 MGI
acts upstream of stem cell proliferation IMP
IMP: 通过突变表型推断
18356246 MGI
acts upstream of or within ureteric peristalsis IGI
IGI: 通过遗传相互作用推断
30478225 MGI
acts upstream of or within ventricular septum morphogenesis IMP
IMP: 通过突变表型推断
18467625 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in cilium IDA
IDA: 通过直接分析推断
27046536 MGI
located in nucleus IDA
IDA: 通过直接分析推断
18534921 MGI
part of transcription regulator complex IPI
IPI: 通过物理相互作用推断
18285513 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

T-box transcription factor TBX3

T-box protein 3

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14279 TBX3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20344 Tbx3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26853 Tbx3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tbx3 NCBI NCBI:6926
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