2. Gene
  3. Hnf1a - HNF1 homeobox A Gene

Hnf1a - HNF1 homeobox A Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: HNF1; LFB1; Tcf1; Hnf-1; Tcf-1; HNF1[a]; Hnf1alpha; HNF1-alpha

基因 ID: 21405 | 基因类型: protein coding

关于 Hnf1a

功能概要

This gene encodes a hepatic transcription factor. The encoded protein is not a member of the T-cell factor family, and is distinct from T-cell specific transcription factor 7 which has also been referred to by the symbol Tcf1. [provided by RefSeq, Jul 2008]

Hnf1a 基因产物(1)

mRNA Protein Name
NM_009327.3 NP_033353.2 hepatocyte nuclear factor 1-alpha
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
1363228 MGI
enables DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
2044952 MGI
enables DNA-binding transcription factor activity IMP
IMP: 通过突变表型推断
8598044 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
11287626 MGI
enables chromatin binding IDA
IDA: 通过直接分析推断
22780989 MGI
enables identical protein binding IPI
IPI: 通过物理相互作用推断
1685988 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
2044952 MGI
enables protein dimerization activity IPI
IPI: 通过物理相互作用推断
11106484 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in D-glucose import IDA
IDA: 通过直接分析推断
11269503 MGI
acts upstream of or within bile acid and bile salt transport IMP
IMP: 通过突变表型推断
11279518 MGI
acts upstream of or within bile acid biosynthetic process IMP
IMP: 通过突变表型推断
11279518 MGI
acts upstream of or within cholesterol metabolic process IMP
IMP: 通过突变表型推断
11279518 MGI
acts upstream of or within chromatin remodeling IMP
IMP: 通过突变表型推断
11733582 MGI
involved in chromatin remodeling IMP
IMP: 通过突变表型推断
12367519 MGI
acts upstream of or within fatty acid biosynthetic process IMP
IMP: 通过突变表型推断
10852923 MGI
acts upstream of or within fatty acid transport IMP
IMP: 通过突变表型推断
10852923 MGI
involved in glucose homeostasis IDA
IDA: 通过直接分析推断
11269503 MGI
acts upstream of or within glucose homeostasis IMP
IMP: 通过突变表型推断
9593777 MGI
acts upstream of or within heme biosynthetic process IMP
IMP: 通过突变表型推断
10617683 MGI
acts upstream of or within insulin secretion IMP
IMP: 通过突变表型推断
9566924 MGI
acts upstream of or within liver development IMP
IMP: 通过突变表型推断
9566924 MGI
acts upstream of or within positive regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
2044952 MGI
involved in positive regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
11269503 MGI
acts upstream of or within positive regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
8598044 MGI
involved in positive regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
12367519 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
15581617 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
11287626 MGI
acts upstream of or within regulation of hormone secretion IMP
IMP: 通过突变表型推断
9566924 MGI
acts upstream of or within regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
9689059 MGI
acts upstream of or within regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
22589549 MGI
involved in renal D-glucose absorption IDA
IDA: 通过直接分析推断
11269503 MGI
acts upstream of or within reproductive structure development IMP
IMP: 通过突变表型推断
9566924 MGI
acts upstream of or within response to glucose IMP
IMP: 通过突变表型推断
9733737 MGI
acts upstream of or within response to oxidative stress IMP
IMP: 通过突变表型推断
10617683 MGI
acts upstream of or within reverse cholesterol transport IMP
IMP: 通过突变表型推断
15793583 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
1363228 MGI
part of transcription regulator complex IPI
IPI: 通过物理相互作用推断
14570708 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

hepatocyte nuclear factor 1-alpha

liver-specific transcription factor LF-B1

transcription factor 1

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06255 HNF1A Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-174669 Human HNF1A mRNA / 否
HY-RS19690 Hnf1a Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26185 Hnf1a Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hnf1a NCBI NCBI:6927
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