2. Gene
  3. Tcf12 - transcription factor 12 Gene

Tcf12 - transcription factor 12 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: HEB; ME1; REB; ALF1; HTF4; HTF-4; HEBAlt; bHLHb20; A130037E08Rik

基因 ID: 21406 | 基因类型: protein coding

关于 Tcf12

功能概要

Enables E-box binding activity and protein heterodimerization activity. Involved in positive regulation of neuron differentiation. Acts upstream of or within positive regulation of gene expression and positive regulation of transcription, DNA-templated. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in craniosynostosis. Orthologous to human TCF12 (transcription factor 12). [provided by Alliance of Genome Resources, Apr 2022]

Tcf12 基因产物(5)

mRNA Protein Name
NM_001253862.1 NP_001240791.1 transcription factor 12 isoform 2
NM_001253863.1 NP_001240792.1 transcription factor 12 isoform 3
NM_001253864.1 NP_001240793.1 transcription factor 12 isoform 4
NM_001253865.1 NP_001240794.1 transcription factor 12 isoform 5
NM_011544.3 NP_035674.2 transcription factor 12 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
1321336 MGI
enables E-box binding IDA
IDA: 通过直接分析推断
18214987 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
1922066 MGI
enables protein heterodimerization activity IDA
IDA: 通过直接分析推断
18214987 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of gene expression IMP
IMP: 通过突变表型推断
18958875 MGI
acts upstream of or within positive regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
1321336 MGI
acts upstream of or within positive regulation of gene expression IMP
IMP: 通过突变表型推断
18958875 MGI
involved in positive regulation of neuron differentiation IDA
IDA: 通过直接分析推断
18214987 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of transcription regulator complex IDA
IDA: 通过直接分析推断
15351717 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

transcription factor 12

DNA-binding protein HTF4

E-box-binding protein

TCF-12

class A helix-loop-helix transcription factor ME1

transcription factor HTF-4

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14299 TCF12 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21063 Tcf12 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27580 Tcf12 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tcf12 NCBI NCBI:6938
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