2. Gene
  3. Slc18a2 - solute carrier family 18 (vesicular monoamine), member 2 Gene

Slc18a2 - solute carrier family 18 (vesicular monoamine), member 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Vmat2; 9330105E13; 1110037L13Rik

基因 ID: 214084 | 基因类型: protein coding

关于 Slc18a2

功能概要

Predicted to enable several functions, including amine transmembrane transporter activity; heat shock protein binding activity; and serotonin:sodium symporter activity. Involved in neurotransmitter loading into synaptic vesicle. Acts upstream of or within several processes, including locomotory behavior; response to amphetamine; and response to toxic substance. Located in dopaminergic synapse. Is expressed in several structures, including adrenal gland; alimentary system; eye; integumental system; and nervous system. Human ortholog(s) of this gene implicated in Parkinson's disease and type 1 diabetes mellitus. Orthologous to human SLC18A2 (solute carrier family 18 member A2). [provided by Alliance of Genome Resources, Apr 2022]

Slc18a2 基因产物(1)

mRNA Protein Name
NM_172523.3 NP_766111.1 synaptic vesicular amine transporter
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
19357284 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in histamine secretion by mast cell IMP
IMP: 通过突变表型推断
10618388 MGI
acts upstream of or within locomotory behavior IMP
IMP: 通过突变表型推断
9275230 MGI
involved in neurotransmitter loading into synaptic vesicle IDA
IDA: 通过直接分析推断
9427251 MGI
involved in neurotransmitter loading into synaptic vesicle IMP
IMP: 通过突变表型推断
9427251 MGI
acts upstream of or within post-embryonic development IMP
IMP: 通过突变表型推断
9275230 MGI
acts upstream of or within response to amphetamine IMP
IMP: 通过突变表型推断
9275230 MGI
acts upstream of or within response to toxic substance IMP
IMP: 通过突变表型推断
9275230 MGI
involved in serotonin secretion by mast cell IMP
IMP: 通过突变表型推断
10618388 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in dopaminergic synapse IDA
IDA: 通过直接分析推断
9427251 MGI
is active in dopaminergic synapse IMP
IMP: 通过突变表型推断
9427251 MGI
located in synaptic vesicle membrane IDA
IDA: 通过直接分析推断
9427251 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

synaptic vesicular amine transporter

VAT2

monoamine transporter

solute carrier family 18 member 2

vesicular amine transporter 2

vesicular monoamine transporter 2

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13044 SLC18A2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22032 Slc18a2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Slc18a2 NCBI NCBI:6571
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