1. Gene
  2. Micu1 - mitochondrial calcium uptake 1 Gene

Micu1 - mitochondrial calcium uptake 1 Gene

种属: Mus musculus

同用名: Calc; Cbara1; C730016L05Rik

基因 ID: 216001 | 基因类型: protein coding

关于 Micu1

功能概要

Enables calcium ion binding activity and protein heterodimerization activity. Predicted to be involved in several processes, including calcium import into the mitochondrion; positive regulation of mitochondrial calcium ion concentration; and regulation of cellular hyperosmotic salinity response. Predicted to act upstream of or within calcium ion transport. Located in mitochondrion. Part of Calcium Channel complex. Is expressed in several structures, including genitourinary system; liver; nervous system; parathyroid gland; and respiratory system. Human ortholog(s) of this gene implicated in myopathy with extrapyramidal signs. Orthologous to human MICU1 (mitochondrial calcium uptake 1). [provided by Alliance of Genome Resources, Apr 2022]

Micu1 基因产物(4)

mRNA Protein Name
NM_001291442.1 NP_001278371.1 calcium uptake protein 1, mitochondrial isoform 1
NM_001291443.1 NP_001278372.1 calcium uptake protein 1, mitochondrial isoform 2
NM_001359267.1 NP_001346196.1 calcium uptake protein 1, mitochondrial isoform 4
NM_144822.3 NP_659071.1 calcium uptake protein 1, mitochondrial isoform 3
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables calcium ion binding IMP
IMP: 通过突变表型推断
24560927 MGI
enables calcium ion sensor activity IDA
IDA: 通过直接分析推断
24560927 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
24560927 MGI
enables protein heterodimerization activity IPI
IPI: 通过物理相互作用推断
24560927 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in calcium import into the mitochondrion IDA
IDA: 通过直接分析推断
27818145 MGI
involved in calcium import into the mitochondrion IMP
IMP: 通过突变表型推断
27477272 MGI
involved in positive regulation of cristae formation IDA
IDA: 通过直接分析推断
37098122 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of calcium channel complex IDA
IDA: 通过直接分析推断
23409044 MGI
is active in mitochondrial inner membrane IDA
IDA: 通过直接分析推断
30504268 MGI
located in mitochondrial intermembrane space IDA
IDA: 通过直接分析推断
30504268 MGI
is active in mitochondrion IDA
IDA: 通过直接分析推断
27818145 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

calcium uptake protein 1, mitochondrial

calcium binding atopy-related autoantigen 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Micu1 NCBI NCBI:10367