2. Gene
  3. Socs2 - suppressor of cytokine signaling 2 Gene

Socs2 - suppressor of cytokine signaling 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: hg; JAB; CIS2; Cish2; SSI-2; SOCS-2; 8030460M17; D130043N08Rik

基因 ID: 216233 | 基因类型: protein coding

关于 Socs2

功能概要

Enables growth hormone receptor binding activity. Acts upstream of or within several processes, including mammary gland development; negative regulation of receptor signaling pathway via JAK-STAT; and positive regulation of neuron differentiation. Predicted to be located in cytoplasm. Predicted to be part of phosphatidylinositol 3-kinase complex. Is expressed in several structures, including lung; primary sex cord; retina; and ureteric tip. Human ortholog(s) of this gene implicated in endometrial Cancer and ovarian carcinoma. Orthologous to human SOCS2 (suppressor of cytokine signaling 2). [provided by Alliance of Genome Resources, Apr 2022]

Socs2 基因产物(4)

mRNA Protein Name
NM_001168655.1 NP_001162126.1 suppressor of cytokine signaling 2
NM_001168656.1 NP_001162127.1 suppressor of cytokine signaling 2
NM_001168657.1 NP_001162128.1 suppressor of cytokine signaling 2
NM_007706.4 NP_031732.1 suppressor of cytokine signaling 2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables growth hormone receptor binding IPI
IPI: 通过物理相互作用推断
15690087 MGI
enables phosphorylation-dependent protein binding IMP
IMP: 通过突变表型推断
15690087 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
31578312 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of cell surface receptor signaling pathway via JAK-STAT IGI
IGI: 通过遗传相互作用推断
16469767 MGI
acts upstream of or within intracellular signal transduction IMP
IMP: 通过突变表型推断
15690087 MGI
acts upstream of or within lactation IGI
IGI: 通过遗传相互作用推断
11445538 MGI
acts upstream of or within lactation IMP
IMP: 通过突变表型推断
11445538 MGI
acts upstream of or within mammary gland alveolus development IGI
IGI: 通过遗传相互作用推断
11445538 MGI
acts upstream of or within mammary gland alveolus development IMP
IMP: 通过突变表型推断
11445538 MGI
involved in negative regulation of growth hormone receptor signaling pathway IMP
IMP: 通过突变表型推断
12040024 MGI
acts upstream of or within negative regulation of multicellular organism growth IGI
IGI: 通过遗传相互作用推断
15690087 MGI
acts upstream of or within negative regulation of multicellular organism growth IMP
IMP: 通过突变表型推断
15690087 MGI
acts upstream of or within negative regulation of receptor signaling pathway via JAK-STAT IGI
IGI: 通过遗传相互作用推断
16469767 MGI
acts upstream of or within positive regulation of neuron differentiation IDA
IDA: 通过直接分析推断
12368809 MGI
acts upstream of or within regulation of multicellular organism growth IMP
IMP: 通过突变表型推断
11401434 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

suppressor of cytokine signaling 2

CIS-2

STAT-induced STAT inhibitor 2

cytokine inducible SH2-containing protein 2

cytokine-inducible SH2 protein 2

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-156395 MN551 Inducer 98.05% 否
HY-173364 EB-TCIP Inducer / 否
HY-RS13553 SOCS2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS18546 Socs2 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS25028 Socs2 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Socs2 NCBI NCBI:8835
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