2. Gene
  3. Tph2 - tryptophan hydroxylase 2 Gene

Tph2 - tryptophan hydroxylase 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Ntph

基因 ID: 216343 | 基因类型: protein coding

关于 Tph2

功能概要

Enables tryptophan 5-monooxygenase activity. Predicted to be involved in aromatic amino acid family metabolic process. Predicted to act upstream of or within serotonin biosynthetic process from tryptophan. Located in neuron projection. Is expressed in early conceptus; germ cell of ovary; nervous system; retina; and tongue. Used to study endogenous depression. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder; autistic disorder; major depressive disorder; and panic disorder. Orthologous to human TPH2 (Tryptophan Hydroxylase 2). [provided by Alliance of Genome Resources, Apr 2022]

Tph2 基因产物(1)

mRNA Protein Name
NM_173391.3 NP_775567.2 tryptophan 5-hydroxylase 2
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables tryptophan 5-monooxygenase activity IDA
IDA: 通过直接分析推断
12511643 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in neuron projection IDA
IDA: 通过直接分析推断
19906978 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

tryptophan 5-hydroxylase 2

neuronal tryptophan hydroxylase

tryptophan 5-monooxygenase 2

相关产品

Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-W019599 4-Chloro-L-phenylalanine Inhibitor ≥98.0% 否
HY-120083 Rodatristat Inhibitor 98.41% 否
HY-157014 TPT-004 Inhibitor 99.90% 否
HY-RS14331 TDO2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS14933 TPH2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17651 Tph2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24111 Tph2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tph2 NCBI NCBI:121278
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