2. Gene
  3. Nlgn2 - neuroligin 2 Gene

Nlgn2 - neuroligin 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: NL2; NLG2

基因 ID: 216856 | 基因类型: protein coding

关于 Nlgn2

功能概要

Enables cell adhesion molecule binding activity; identical protein binding activity; and neurexin family protein binding activity. Involved in several processes, including modulation of chemical synaptic transmission; regulation of signal transduction; and synapse organization. Acts upstream of or within several processes, including GABAergic synaptic transmission; protein localization to cell surface; and regulation of respiratory gaseous exchange by nervous system process. Located in GABA-ergic synapse; cell surface; and dopaminergic synapse. Is active in glycinergic synapse. Is integral component of postsynaptic specialization membrane. Is expressed in brainstem. Used to study schizophrenia. Orthologous to human NLGN2 (neuroligin 2). [provided by Alliance of Genome Resources, Apr 2022]

Nlgn2 基因产物(2)

mRNA Protein Name
NM_001364137.1 NP_001351066.1 neuroligin-2 precursor
NM_198862.2 NP_942562.2 neuroligin-2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables cell adhesion molecule binding IPI
IPI: 通过物理相互作用推断
21424692 MGI
enables identical protein binding IPI
IPI: 通过物理相互作用推断
18250328 MGI
enables neurexin family protein binding IPI
IPI: 通过物理相互作用推断
21424692 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
19816407 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in gephyrin clustering involved in postsynaptic density assembly IDA
IDA: 通过直接分析推断
15620359 MGI
acts upstream of or within gephyrin clustering involved in postsynaptic density assembly IGI
IGI: 通过遗传相互作用推断
29107521 MGI
acts upstream of or within gephyrin clustering involved in postsynaptic density assembly IMP
IMP: 通过突变表型推断
29107521 MGI
involved in inhibitory synapse assembly IDA
IDA: 通过直接分析推断
22960622 MGI
involved in locomotory exploration behavior IMP
IMP: 通过突变表型推断
19016888 MGI
acts upstream of or within modulation of chemical synaptic transmission IGI
IGI: 通过遗传相互作用推断
16982420 MGI
involved in neuromuscular process controlling balance IMP
IMP: 通过突变表型推断
19016888 MGI
acts upstream of or within neurotransmitter-gated ion channel clustering IDA
IDA: 通过直接分析推断
29107521 MGI
acts upstream of or within neurotransmitter-gated ion channel clustering IGI
IGI: 通过遗传相互作用推断
29107521 MGI
acts upstream of or within neurotransmitter-gated ion channel clustering IMP
IMP: 通过突变表型推断
29107521 MGI
involved in positive regulation of excitatory postsynaptic potential IMP
IMP: 通过突变表型推断
15620359 MGI
involved in positive regulation of inhibitory postsynaptic potential IMP
IMP: 通过突变表型推断
15620359 MGI
involved in positive regulation of synaptic transmission, GABAergic IMP
IMP: 通过突变表型推断
15620359 MGI
involved in positive regulation of synaptic transmission, glutamatergic IMP
IMP: 通过突变表型推断
15620359 MGI
involved in positive regulation of synaptic vesicle clustering IDA
IDA: 通过直接分析推断
15620359 MGI
involved in postsynaptic density protein 95 clustering IDA
IDA: 通过直接分析推断
15620359 MGI
involved in postsynaptic membrane assembly IDA
IDA: 通过直接分析推断
15620359 MGI
involved in postsynaptic specialization assembly IDA
IDA: 通过直接分析推断
15620359 MGI
involved in postsynaptic specialization assembly IMP
IMP: 通过突变表型推断
15620359 MGI
acts upstream of or within presynapse assembly IDA
IDA: 通过直接分析推断
23358245 MGI
involved in presynaptic membrane assembly IDA
IDA: 通过直接分析推断
15620359 MGI
involved in presynaptic membrane assembly IMP
IMP: 通过突变表型推断
19016888 MGI
acts upstream of or within protein localization to cell surface IDA
IDA: 通过直接分析推断
29107521 MGI
acts upstream of or within protein localization to cell surface IMP
IMP: 通过突变表型推断
29107521 MGI
involved in protein localization to synapse IDA
IDA: 通过直接分析推断
15620359 MGI
involved in regulation of AMPA receptor activity IMP
IMP: 通过突变表型推断
15620359 MGI
acts upstream of or within regulation of respiratory gaseous exchange by nervous system process IGI
IGI: 通过遗传相互作用推断
16982420 MGI
involved in sensory perception of pain IMP
IMP: 通过突变表型推断
19016888 MGI
acts upstream of or within synaptic transmission, GABAergic IDA
IDA: 通过直接分析推断
29107521 MGI
acts upstream of or within synaptic transmission, GABAergic IGI
IGI: 通过遗传相互作用推断
29107521 MGI
acts upstream of or within synaptic transmission, GABAergic IMP
IMP: 通过突变表型推断
29107521 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in GABA-ergic synapse IDA
IDA: 通过直接分析推断
15620359 MGI
located in GABA-ergic synapse IDA
IDA: 通过直接分析推断
29107521 MGI
is active in GABA-ergic synapse IMP
IMP: 通过突变表型推断
15620359 MGI
is active in axon IDA
IDA: 通过直接分析推断
23358245 MGI
is active in cell surface IDA
IDA: 通过直接分析推断
23358245 MGI
located in cell surface IDA
IDA: 通过直接分析推断
29107521 MGI
is active in dendrite IDA
IDA: 通过直接分析推断
23358245 MGI
is active in dopaminergic synapse IDA
IDA: 通过直接分析推断
27035941 MGI
is active in glycinergic synapse IDA
IDA: 通过直接分析推断
19755106 MGI
is active in glycinergic synapse IMP
IMP: 通过突变表型推断
19755106 MGI
is active in postsynaptic specialization membrane IDA
IDA: 通过直接分析推断
27035941 MGI
located in synapse IDA
IDA: 通过直接分析推断
15681343 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

neuroligin-2

ortholog of human and rat neuroligin 2 NLGN2

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09340 NLGN2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22679 Nlgn2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS29193 Nlgn2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nlgn2 NCBI NCBI:57555
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z