2. Gene
  3. Trim25 - tripartite motif-containing 25 Gene

Trim25 - tripartite motif-containing 25 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: EFP; Zfp147

基因 ID: 217069 | 基因类型: protein coding

关于 Trim25

功能概要

Predicted to enable RIG-I binding activity; transcription coactivator activity; and ubiquitin protein Ligase activity. Involved in defense response to Other organism; negative regulation of viral entry into host cell; and regulation of protein localization. Acts upstream of or within cellular response to Leukemia Inhibitory Factor. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human TRIM25 (tripartite motif containing 25). [provided by Alliance of Genome Resources, Apr 2022]

Trim25 基因产物(1)

mRNA Protein Name
NM_009546.2 NP_033572.2 E3 ubiquitin/ISG15 ligase TRIM25
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
29125140 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: 通过表达模式推断
20439489 MGI
involved in innate immune response IDA
IDA: 通过直接分析推断
18248090 MGI
involved in negative regulation of viral entry into host cell IDA
IDA: 通过直接分析推断
18248090 MGI
involved in regulation of protein localization IMP
IMP: 通过突变表型推断
29125140 MGI
involved in suppression of viral release by host IDA
IDA: 通过直接分析推断
18248090 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
11331580 MGI
located in nucleus IDA
IDA: 通过直接分析推断
29125140 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

E3 ubiquitin/ISG15 ligase TRIM25

RING-type E3 ubiquitin transferase TRIM25

estrogen-responsive finger protein

tripartite motif protein 25

tripartite motif-containing protein 25

ubiquitin/ISG15-conjugating enzyme TRIM25

zinc finger protein 147

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-162065 N6F11 Inducer 98.37% 否
HY-RS15030 TRIM25 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-174853 TRIM25 ligand-1 Ligand / 否
HY-RS18314 Trim25 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24792 Trim25 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Trim25 NCBI NCBI:7706
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