2. Gene
  3. Tgif1 - TGFB-induced factor homeobox 1 Gene

Tgif1 - TGFB-induced factor homeobox 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Tgif

基因 ID: 21815 | 基因类型: protein coding

关于 Tgif1

功能概要

Enables chromatin binding activity. Acts upstream of or within several processes, including negative regulation of retinoic acid receptor signaling pathway; nodal signaling pathway; and positive regulation of fibroblast proliferation. Located in nucleus. Is expressed in several structures, including alimentary system; brain; early conceptus; embryo ectoderm; and genitourinary system. Used to study otitis media. Human ortholog(s) of this gene implicated in holoprosencephaly and holoprosencephaly 4. Orthologous to human TGIF1 (TGFB induced factor homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

Tgif1 基因产物(5)

mRNA Protein Name
NM_001164074.1 NP_001157546.1 homeobox protein TGIF1 isoform c
NM_001164075.1 NP_001157547.1 homeobox protein TGIF1 isoform a
NM_001164076.1 NP_001157548.1 homeobox protein TGIF1 isoform c
NM_001164077.1 NP_001157549.1 homeobox protein TGIF1 isoform c
NM_009372.3 NP_033398.2 homeobox protein TGIF1 isoform b
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables chromatin binding IDA
IDA: 通过直接分析推断
16428452 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
16428452 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of amacrine cell differentiation IDA
IDA: 通过直接分析推断
18973577 MGI
acts upstream of cell population proliferation IMP
IMP: 通过突变表型推断
17082251 MGI
acts upstream of or within determination of left/right symmetry IMP
IMP: 通过突变表型推断
16705179 MGI
acts upstream of or within dorsal/ventral pattern formation IMP
IMP: 通过突变表型推断
17082251 MGI
acts upstream of fibroblast proliferation IMP
IMP: 通过突变表型推断
16705179 MGI
acts upstream of or within negative regulation of cell population proliferation IMP
IMP: 通过突变表型推断
17082251 MGI
acts upstream of or within negative regulation of retinoic acid receptor signaling pathway IMP
IMP: 通过突变表型推断
16428452 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
16428452 MGI
acts upstream of or within neural tube closure IMP
IMP: 通过突变表型推断
17082251 MGI
acts upstream of neuron differentiation IDA
IDA: 通过直接分析推断
18973577 MGI
acts upstream of or within nodal signaling pathway IGI
IGI: 通过遗传相互作用推断
20040491 MGI
acts upstream of or within positive regulation of amacrine cell differentiation IDA
IDA: 通过直接分析推断
18973577 MGI
acts upstream of or within positive regulation of fibroblast proliferation IMP
IMP: 通过突变表型推断
16705179 MGI
acts upstream of or within regulation of gastrulation IGI
IGI: 通过遗传相互作用推断
20040491 MGI
acts upstream of or within retina development in camera-type eye IDA
IDA: 通过直接分析推断
18973577 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
21503901 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

homeobox protein TGIF1

5'-TG-3'-interacting factor 1

TALE family homeobox

TG interacting factor 1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14455 TGIF1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20113 Tgif1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26617 Tgif1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tgif1 NCBI NCBI:7050
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