2. Gene
  3. Kdm1b - lysine (K)-specific demethylase 1B Gene

Kdm1b - lysine (K)-specific demethylase 1B Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Aof1; 4632428N09Rik

基因 ID: 218214 | 基因类型: protein coding

关于 Kdm1b

功能概要

Enables flavin adenine dinucleotide binding activity; histone H3-di/monomethyl-lysine-4 FAD-dependent demethylase activity; and zinc ion binding activity. Involved in regulation of DNA methylation. Acts upstream of or within DNA methylation involved in gamete generation; histone H3-K4 demethylation; and regulation of gene expression by genetic imprinting. Located in nucleus. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human KDM1B (lysine demethylase 1B). [provided by Alliance of Genome Resources, Apr 2022]

Kdm1b 基因产物(3)

mRNA Protein Name
NM_001402908.1 NP_001389837.1 lysine-specific histone demethylase 1B isoform 2
NM_001402909.1 NP_001389838.1 lysine-specific histone demethylase 1B isoform 3
NM_172262.4 NP_758466.1 lysine-specific histone demethylase 1B isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables FAD-dependent H3K4me/H3K4me3 demethylase activity IDA
IDA: 通过直接分析推断
19407342 MGI
enables flavin adenine dinucleotide binding IDA
IDA: 通过直接分析推断
19407342 MGI
enables histone H3K4 demethylase activity IDA
IDA: 通过直接分析推断
19407342 MGI
NOT enables histone H3K4me/H3K4me2/H3K4me3 demethylase activity IDA
IDA: 通过直接分析推断
19407342 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
22878500 MGI
enables zinc ion binding IDA
IDA: 通过直接分析推断
19407342 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within epigenetic programing of female pronucleus IMP
IMP: 通过突变表型推断
19727073 MGI
acts upstream of or within genomic imprinting IMP
IMP: 通过突变表型推断
19727073 MGI
involved in genomic imprinting IMP
IMP: 通过突变表型推断
19727073 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
19727073 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

lysine-specific histone demethylase 1B

amine oxidase, flavin containing 1

flavin-containing amine oxidase domain-containing protein 1

lysine-specific histone demethylase 2

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07208 KDM1B Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21615 Kdm1b Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28133 Kdm1b Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Kdm1b NCBI NCBI:221656
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