2. Gene
  3. Tia1 - cytotoxic granule-associated RNA binding protein 1 Gene

Tia1 - cytotoxic granule-associated RNA binding protein 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: TIA-1; mTIA-1; 2310050N03Rik

基因 ID: 21841 | 基因类型: protein coding

关于 Tia1

功能概要

Enables mRNA 3'-UTR AU-rich region binding activity. Acts upstream of or within negative regulation of cytokine production and negative regulation of translation. Located in cytoplasmic stress granule and nuclear stress granule. Is expressed in several structures, including alimentary system; central nervous system; metanephros; respiratory system; and sensory organ. Orthologous to human TIA1 (TIA1 cytotoxic granule associated RNA binding protein). [provided by Alliance of Genome Resources, Apr 2022]

Tia1 基因产物(3)

mRNA Protein Name
NM_001164078.1 NP_001157550.1 cytotoxic granule associated RNA binding protein TIA1 isoform 2
NM_001164079.1 NP_001157551.1 cytotoxic granule associated RNA binding protein TIA1 isoform 3
NM_011585.4 NP_035715.1 cytotoxic granule associated RNA binding protein TIA1 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables mRNA 3'-UTR AU-rich region binding IDA
IDA: 通过直接分析推断
10921895 MGI
enables mRNA 3'-UTR binding IDA
IDA: 通过直接分析推断
16227602 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within negative regulation of cytokine production IMP
IMP: 通过突变表型推断
10921895 MGI
involved in negative regulation of translation IDA
IDA: 通过直接分析推断
16227602 MGI
acts upstream of or within negative regulation of translation IMP
IMP: 通过突变表型推断
10921895 MGI
involved in regulation of alternative mRNA splicing, via spliceosome IDA
IDA: 通过直接分析推断
10938105 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
11514562 MGI
located in cytoplasmic stress granule IDA
IDA: 通过直接分析推断
21933836 MGI
located in nuclear stress granule IDA
IDA: 通过直接分析推断
22022532 MGI
located in nucleus IDA
IDA: 通过直接分析推断
12388085 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

cytotoxic granule associated RNA binding protein TIA1

nucleolysin TIA-1

RNA-binding protein TIA-1

T-cell-restricted intracellular antigen-1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14513 TIA1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20825 Tia1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27339 Tia1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tia1 NCBI NCBI:7072
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