1. Gene
  2. Tkt - transketolase Gene

Tkt - transketolase Gene

种属: Mus musculus

同用名: p68

基因 ID: 21881 | 基因类型: protein coding

关于 Tkt

功能概要

This gene encodes an enzyme that binds magnesium and thiamine pyrophosphate and catalyzes the transfer of sugar phosphates to an aldose acceptor. This enzyme is a key component of the pentose phosphate pathway during glycolysis. It is significantly expressed in the cornea and may be involved in the cellular response against oxidative stress. Haploinsufficiency of this gene leads to decreased growth and reduction of adipose tissue. [provided by RefSeq, Dec 2013]

Tkt 基因产物(1)

mRNA Protein Name
NM_009388.6 NP_033414.1 transketolase
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables transketolase activity IDA
IDA: 通过直接分析推断
5360673 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in pentose-phosphate shunt IDA
IDA: 通过直接分析推断
5360673 MGI
involved in pentose-phosphate shunt, non-oxidative branch IMP
IMP: 通过突变表型推断
32295803 MGI
acts upstream of or within regulation of growth IMP
IMP: 通过突变表型推断
12167708 MGI
involved in xylulose 5-phosphate biosynthetic process IDA
IDA: 通过直接分析推断
5360673 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in cytosol IDA
IDA: 通过直接分析推断
5360673 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

transketolase

TK

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tkt NCBI NCBI:7086
Rattus norvegicus Tkt NCBI NCBI:64524
Macaca mulatta Tkt NCBI NCBI:694327