1. Gene
  2. Tnnc1 - troponin C, cardiac/slow skeletal Gene

Tnnc1 - troponin C, cardiac/slow skeletal Gene

种属: Mus musculus

同用名: TnC; cTnC; cTnI; tncc

基因 ID: 21924 | 基因类型: protein coding

关于 Tnnc1

功能概要

Enables actin filament binding activity. Involved in regulation of ATPase activity and regulation of muscle filament sliding speed. Acts upstream of or within transition between fast and slow fiber. Predicted to be located in contractile fiber. Predicted to be part of cardiac Troponin complex. Is expressed in several structures, including alimentary system; heart; liver; metanephros; and skeletal muscle. Used to study hypertrophic cardiomyopathy 13. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 1Z; hypertrophic cardiomyopathy; and hypertrophic cardiomyopathy 13. Orthologous to human TNNC1 (troponin C1, slow skeletal and cardiac type). [provided by Alliance of Genome Resources, Apr 2022]

Tnnc1 基因产物(1)

mRNA Protein Name
NM_009393.4 NP_033419.1 troponin C, slow skeletal and cardiac muscles
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables actin filament binding IDA
IDA: 通过直接分析推断
8785301 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in regulation of ATP-dependent activity IDA
IDA: 通过直接分析推断
8785301 MGI
involved in regulation of muscle filament sliding speed IMP
IMP: 通过突变表型推断
10747195 MGI
acts upstream of or within transition between fast and slow fiber IDA
IDA: 通过直接分析推断
18978355 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

troponin C, slow skeletal and cardiac muscles

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tnnc1 NCBI NCBI:7134