2. Gene
  3. SLC37A2 - solute carrier family 37 member 2 Gene

SLC37A2 - solute carrier family 37 member 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：溶质载体家族 37 成员 2

种属: Homo sapiens

同用名: SPX2; pp11662

基因 ID: 219855 | 基因类型: protein coding

关于 SLC37A2

Cytogenetic location: 11q24.2 Genomic coordinates (GRCh38): 11:125,063,305-125,090,516 (from NCBI)

This gene has 6 transcripts (splice variants), 241 orthologues and 12 paralogues. Broad expression in adrenal (RPKM 13.0), salivary gland (RPKM 12.4) and 18 other tissues.

功能概要

启用葡萄糖 6-磷酸：无机磷酸盐逆向转运活性。参与葡萄糖-6-磷酸转运和磷酸根离子跨膜转运。是内质网膜的组成部分。 [由基因组资源联盟提供，2022 年 4 月]

Enables glucose 6-phosphate:inorganic phosphate antiporter activity. Involved in glucose-6-phosphate transport and phosphate ion transmembrane transport. Is integral component of endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2022]

SLC37A2 基因产物(2)

mRNA Protein Name
NM_001145290.2 NP_001138762.1 glucose-6-phosphate exchanger SLC37A2 isoform 2
NM_198277.3 NP_938018.1 glucose-6-phosphate exchanger SLC37A2 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables glucose 6-phosphate:phosphate antiporter activity EXP
EXP: 通过实验结果推断
21949678 GOA
enables glucose 6-phosphate:phosphate antiporter activity IDA
IDA: 通过直接分析推断
21949678 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in glucose-6-phosphate transport IDA
IDA: 通过直接分析推断
21949678 GOA
involved in phosphate ion transmembrane transport IDA
IDA: 通过直接分析推断
21949678 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endoplasmic reticulum membrane IDA
IDA: 通过直接分析推断
21949678 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SLC37A2 蛋白结构

MFS_1

MFS_1: Major Facilitator Superfamily (92 - 414)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 501 a.a.
蛋白主名 其他名称

glucose-6-phosphate exchanger SLC37A2

solute carrier family 37 (glucose-6-phosphate transporter), member 2

关联疾病

疾病名称 别名
Caffey Disease

Infantile Cortical Hyperostosis

CAFYD

Cortical Congenital Hyperostosis

Caffey-Silverman Syndrome

De Toni-Caffey Disease

Hyperostosis Cortical Infantile

Hyperostosis, Cortical, Congenital
Van Den Ende-Gupta Syndrome

VDEGS

Blepharophimosis, Arachnodactyly, And Congenital Contractures

Marden-Walker-Like Syndrome

Marden-Walker-Like Syndrome Without Psychomotor Retardation

Marden Walker Like Syndrome

Marden-Walker-Like Syndrome Without Psychmotor Retardation

Van Den Ende Gupta Syndrome

Marden Walker Like Syndrome Without Psychomotor Retardation

Blepharophimosis Arachnodactyly And Congenital Contractures
Combined Oxidative Phosphorylation Deficiency 24

COXPD24

Combined Oxidative Phosphorylation Defect Type 24

Oxidative Phosphorylation Deficiency, Combined, Type 24
Combined Oxidative Phosphorylation Deficiency 20

COXPD20

Combined Oxidative Phosphorylation Defect Type 20

Oxidative Phosphorylation Deficiency, Combined, Type 20
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-119384 Promegestone Agonist ≥98.0% 否
HY-RS13214 SLC37A2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18882 Slc37a2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25373 Slc37a2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus SLC37A2 VGNC VGNC:34843
Mus musculus SLC37A2 MGD MGI:1929693
Macaca mulatta SLC37A2 VGNC VGNC:107645
Felis catus SLC37A2 VGNC VGNC:81937
Canis familiaris SLC37A2 VGNC VGNC:46387
Rattus norvegicus SLC37A2 RGD RGD:1564160
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