2. Gene
  3. DDIAS - DNA damage induced apoptosis suppressor Gene

DDIAS - DNA damage induced apoptosis suppressor Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：DNA 损伤诱导凋亡抑制因子

种属: Homo sapiens

同用名: noxin; C11orf82

基因 ID: 220042 | 基因类型: protein coding

关于 DDIAS

Cytogenetic location: 11q14.1 Genomic coordinates (GRCh38): 11:82,901,736-82,934,659 (from NCBI)

This gene has 12 transcripts (splice variants) and 92 orthologues. Broad expression in testis (RPKM 5.9), lymph node (RPKM 1.9) and 14 other tissues.

功能概要

参与响应 DNA 损伤的内在凋亡信号通路的负调节和 DNA 稳定性的调节。预计在细胞质和细胞核中有活性。 [由基因组资源联盟提供，2022 年 4 月]

Involved in negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage and regulation of DNA stability. Predicted to be active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

DDIAS 基因产物(2)

mRNA Protein Name
NM_001363481.2 NP_001350410.1 DNA damage-induced apoptosis suppressor protein
NM_145018.4 NP_659455.3 DNA damage-induced apoptosis suppressor protein
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage IMP
IMP: 通过突变表型推断
24214091 GOA
involved in regulation of DNA stability IMP
IMP: 通过突变表型推断
24214091 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

DNA damage-induced apoptosis suppressor protein

nitric oxide-inducible gene protein

关联疾病

疾病名称 别名
Fanconi Anemia, Complementation Group I

Fanconi Anemia Complementation Group I

FANCI
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03613 DDIAS Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta DDIAS VGNC VGNC:71718
Mus musculus DDIAS MGD MGI:1921291
Bos taurus DDIAS VGNC VGNC:27946
Rattus norvegicus DDIAS RGD RGD:1559690
Canis familiaris DDIAS VGNC VGNC:39835
Felis catus DDIAS VGNC VGNC:82007
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